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NIOSH

ISOPROPANOLAMINE

ICSC: 0905

1-Amino-2-propanol
Threamine
C3H9NO / CH3CHOHCH2NH2
Molecular mass: 75.11
ICSC # 0905 		CAS # 78-96-6
RTECS # UA5775000
UN # 2735
EC # 603-082-00-1
November 04, 1997 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Above 77°C explosive vapour/air mixtures may be formed.
Above 77°C use a closed system, ventilation.

EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
•INHALATION Sore throat. Cough. Burning sensation. Shortness of breath. Laboured breathing. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention.
•SKIN Pain. Redness. Blisters. Skin burns.
Protective gloves. Protective clothing.
First rinse with plenty of water, then remove contaminated clothes and rinse again. Refer for medical attention.
•EYES Pain. Redness. Severe deep burns. Loss of vision.
Face shield, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Burning sensation. Abdominal cramps. Shock or collapse.
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. (Extra personal protection: complete protective clothing including self-contained breathing apparatus).
Separated from strong oxidants, food and feedstuffs. Well closed. Keep in a well-ventilated room.
Do not transport with food and feedstuffs.
C symbol
R: 34
S: 1/2-23-26-36-45
UN Hazard Class: 8
UN Packing Group: II
ICSC: 0905 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

ISOPROPANOLAMINE

ICSC: 0905

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
On combustion, forms nitrogen oxides. Reacts with strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: IIb (not established but data is available) (DFG 2008).


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is corrosive to the eyes, the skin and the respiratory tract. Inhalation of vapours may cause lung oedema (see Notes). Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Boiling point: 159.5°C
Melting point: -2°C
Relative density (water = 1): 0.96
Solubility in water: soluble
Vapour pressure, kPa at 20°C: <0.2
Relative vapour density (air = 1): 2.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 77°C
Auto-ignition temperature: 374°C
Octanol/water partition coefficient as log Pow: -1.0

ENVIRONMENTAL
DATA


N O T E S

The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered.
Transport Emergency Card: TEC (R)-80G20

NFPA Code: H2; F2; R0;
Card has been partially updated in November 2008: see Occupational Exposure Limits.

ADDITIONAL INFORMATION



ICSC: 0905 ISOPROPANOLAMINE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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