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NIOSH

GUANIDINE HYDROCHLORIDE

ICSC: 0894

Aminoformamidine hydrochloride
Aminomethanamidine hydrochloride
Carbamidine hydrochloride
Iminourea hydrochloride
CH6ClN3 / CH5N3°ClH
Molecular mass: 95.5
ICSC # 0894 		CAS # 50-01-1
RTECS # MF4300000
EC # 607-148-00-0
April 10, 2000 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible.
NO open flames.
Foam, powder.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST!

•INHALATION Cough.
Local exhaust or breathing protection.
Fresh air, rest.
•SKIN Redness.
Protective gloves. Protective clothing.
Rinse skin with plenty of water or shower.
•EYES Redness. Pain.
Safety goggles, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Diarrhoea.
Do not eat, drink, or smoke during work.
Rinse mouth. Give plenty of water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!).

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. (Extra personal protection: P2 filter respirator for harmful particles).
Well closed. Dry.

Xn symbol
R: 22-36/38
S: 2-22
ICSC: 0894 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

GUANIDINE HYDROCHLORIDE

ICSC: 0894

I

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A

N

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D

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A

PHYSICAL STATE; APPEARANCE:
HYGROSCOPIC , CRYSTALLINE POWDER

PHYSICAL DANGERS:


CHEMICAL DANGERS:
On combustion, forms toxic and corrosive fumes including hydrogen chloride and nitrogen oxides . The solution in water is a weak acid.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK not established.


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes and the skin .

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Melting point: 178-185°C
Density: 1.3
g/cm3
Solubility in water, g/100 ml at 20°C: 215
Octanol/water partition coefficient as log Pow: -1.7

ENVIRONMENTAL
DATA


N O T E S

Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.

ADDITIONAL INFORMATION



ICSC: 0894 GUANIDINE HYDROCHLORIDE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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