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NIOSH

DEMETON (MIXED ISOMERS)

ICSC: 0861

(C2H5O)2PS•OCH2CH2SC2H5 and (C2H5O)2PO•SCH2CH2SC2H5
Molecular mass: 258.34
ICSC # 0861 		CAS # 8065-48-3
RTECS # TF3150000
UN # 3018
EC # 015-118-00-8
September 10, 2002 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Liquid formulations containing organic solvents may be flammable.
NO open flames.
Water spray, foam, carbon dioxide, alcohol-resistant foam, dry powder.
EXPLOSION


EXPOSURE
PREVENT GENERATION OF MISTS! AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
•INHALATION Convulsions. Dizziness. Laboured breathing. Nausea. Vomiting. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
•SKIN MAY BE ABSORBED! (Further see Inhalation).
Protective clothing. Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
•EYES LIQUID OR AEROSOL WILL BE ABSORBED! Redness. Pain.
Face shield. or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Abdominal cramps. Diarrhoea. Vomiting. (See Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Give a slurry of activated charcoal in water to drink. See Notes. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. Chemical protection suit including self-contained breathing apparatus.
Separated from strong oxidants, food and feedstuffs . Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Do not transport with food and feedstuffs.
T+ symbol
N symbol
R: 27/28-50
S: 1/2-28-36/37-45-61
UN Hazard Class: 6.1
UN Subsidiary Risks: 3
UN Packing Group: I
ICSC: 0861 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

DEMETON (MIXED ISOMERS)

ICSC: 0861

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on burning producing toxic fumes including phosphorous oxides and sulfur oxides . Reacts violently with strong oxidants. Attacks plastic.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.05 mg/m3 as TWA; (skin); BEI issued; (ACGIH 2002).
MAK: IIb (not established but data is available); skin absorption (H); (DFG 2008). \MAK: IIb (see Notes);H;(DFG 2002).
OSHA PEL: TWA 0.1 mg/m3 skin
NIOSH REL: TWA 0.1 mg/m3 skin
NIOSH IDLH: 10 mg/m3 See: 8065483


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the nervous system , resulting in cardiac disorders , convulsions , cyanosis and respiratory failure . Cholinesterase inhibition. Exposure may result in death. Medical observation is indicated. The effects may be delayed.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.

PHYSICAL
PROPERTIES

Boiling point at 0.27kPa: 134°C
Relative density (water = 1): 1.1
Solubility in water: poor
Vapour pressure, Pa at 20°C: <10
Auto-ignition temperature: 464°C

ENVIRONMENTAL
DATA

The substance is very toxic to aquatic organisms. This substance may be hazardous in the environment; special attention should be given to birds,honey bees and mammals. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal.

N O T E S

This substance is a mixture of two isomers: Demeton-O and Demeton-S (see ICSC 0864). Do NOT take working clothes home. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Depending on the degree of exposure, periodic medical examination is suggested. Carrier solvents used in commercial formulations may change physical and toxicological properties.
Transport Emergency Card: TEC (R)-61GT6-I
Card has been partially updated in November 2008: see Occupational Exposure Limits, Storage.

ADDITIONAL INFORMATION



ICSC: 0861 DEMETON (MIXED ISOMERS)
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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