Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content
NIOSH

2-(ACETYLOXY)BENZOIC ACID

ICSC: 0822

Acetylsalicylic acid
2-Acetoxybenzoic acid
Aspirin
C9H8O4 / CH3COOC6H4COOH
Molecular mass: 180.2
ICSC # 0822 		CAS # 50-78-2
RTECS # VO0700000
March 26, 1998 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible.
NO open flames.
Powder, water spray, foam, carbon dioxide.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST!

•INHALATION Cough. Sore throat.
Ventilation (not if powder).
Fresh air, rest. Refer for medical attention.
•SKIN Redness.
Protective gloves.
Rinse skin with plenty of water or shower. Refer for medical attention.
•EYES Redness. Pain.
Safety goggles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Nausea. Vomiting.
Do not eat, drink, or smoke during work.
Rinse mouth. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Personal protection: P2 filter respirator for harmful particles.
Well closed.

ICSC: 0822 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

2-(ACETYLOXY)BENZOIC ACID

ICSC: 0822

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
COLOURLESS TO WHITE CRYSTALS OR WHITE CRYSTALLINE POWDER , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
The solution in water is a weak acid.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 5 mg/m3 (ACGIH 1997).
MAK not established.
OSHA PEL†: none
NIOSH REL: TWA 5 mg/m3
NIOSH IDLH: N.D. See: IDLH INDEX


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes, the skin, and the respiratory tract. The substance may cause effects on the blood and central nervous system, if ingested in large amounts.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Animal tests show that this substance possibly causes toxic effects upon human reproduction.

PHYSICAL
PROPERTIES

Decomposes below boiling point at 140°C
Melting point: 135°C
Density: 1.4
g/cm3
Solubility in water: poor (0.25 g/100 ml at 15°C)
Vapour pressure, Pa at 25°C: about 0.004
Octanol/water partition coefficient as log Pow: 1.19

ENVIRONMENTAL
DATA


N O T E S

Acenterine, Acesal, Acetol, Acetophen, Acetosal, Acetosalin, Acetylin, Acetylsal, Acisal, Acylpyrin, Asagran, Aspro, Asteric, Caprin, Duramax, Ecotrin, Empirin, Neuronika, Polopiryna, Rhodine, Salacetin, Xaxa are trade names.
Transport Emergency Card: TEC (R)-61G12c

ADDITIONAL INFORMATION



ICSC: 0822 2-(ACETYLOXY)BENZOIC ACID
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
Top