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NIOSH

FENTHION

ICSC: 0655

O,O-Dimethyl-O-(4-methylthio-m-tolyl) phosphorothioate
Phosphorothioic acid, O,O-dimethyl O-(3-methyl-4-(methylthio)phenyl) ester
C10H15O3PS2 / (H3CO)2PSOC6H3(CH3)SCH3
Molecular mass: 278.3
ICSC # 0655 		CAS # 55-38-9
RTECS # TF9625000
UN # 3018
EC # 015-048-00-8
October 11, 2006 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray, foam, powder, carbon dioxide.
EXPLOSION


EXPOSURE
PREVENT GENERATION OF MISTS! STRICT HYGIENE!
IN ALL CASES CONSULT A DOCTOR!
•INHALATION Dizziness. Nausea. Vomiting. Sweating. Pupillary constriction, muscle cramp, excessive salivation. Laboured breathing. Convulsions. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer immediately for medical attention.
•SKIN MAY BE ABSORBED! (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention. Wear protective gloves when administering first aid.
•EYES Blurred vision.
Face shield, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Abdominal cramps. Diarrhoea. Nausea. Vomiting. (Further see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Personal protection: A/P2 filter respirator for organic vapour and harmful dust. Chemical protection suit. and protective gloves. Collect leaking liquid in sealable containers. Absorb remaining liquid in dry sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment.
Separated from strong oxidants, food and feedstuffs . Well closed. Keep in a well-ventilated room. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.
Do not transport with food and feedstuffs.
Severe
marine pollutant.
T symbol
N symbol
R: 21/22-23-48/25-50/53-68
S: 1/2-36/37-45-60-61
UN Hazard Class: 6.1
UN Packing Group: III
Signal: Danger
Skull-Health haz-Enviro
Toxic if swallowed
Toxic in contact with skin
Causes damage to the nervous system
Very toxic to aquatic life
ICSC: 0655 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

FENTHION

ICSC: 0655

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
COLOURLESS OILY LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes including phosphorus oxides and sulfur oxides . Reacts with oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.05 mg/m3 as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2006).
MAK: 0.2 (Inhalable fraction) mg/m3;
Peak limitation category: II(2);
skin absorption (H); (DFG 2006).
OSHA PEL†: none
NIOSH REL: See Appendix D
NIOSH IDLH: N.D. See: IDLH INDEX


ROUTES OF EXPOSURE:
The substance can be absorbed into the body in hazardous amounts by inhalation, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C ; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
Cholinesterase inhibitor. The substance may cause effects on the nervous system , resulting in convulsions and respiratory failure . The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.

PHYSICAL
PROPERTIES

Decomposes when heated
Melting point: 7.5°C
Relative density (water = 1): 1.25
Solubility in water, g/100 ml: 0.005
Vapour pressure, Pa at 25°C: negligible
Relative vapour density (air = 1): 9.6
Flash point: 170°C
Auto-ignition temperature: 365°C
Octanol/water partition coefficient as log Pow: 3.17-4.8

ENVIRONMENTAL
DATA

The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal.

N O T E S

The technical grade (95-98% pure) is a yellow to brown oil with a weak garlic-like odour. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Transport Emergency Card: TEC (R)-61GT6-III

ADDITIONAL INFORMATION



ICSC: 0655 FENTHION
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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