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NIOSH

ASCORBIC ACID

ICSC: 0379

Vitamin C
L-Ascorbic acid
L-Xyloascorbic acid
3-Oxo-L-gulofuranolactone (enol form)
C6H8O6
Molecular mass: 176.12
ICSC # 0379 		CAS # 50-81-7
RTECS # CI7650000
June 10, 1997 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible.
NO open flames.
Water spray, powder.
EXPLOSION


EXPOSURE
PREVENT DISPERSION OF DUST!

•INHALATION Cough. Sore throat.
Local exhaust or breathing protection.
Fresh air, rest.
•SKIN Redness.
Protective gloves.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
•EYES Redness. Pain.
Safety spectacles.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION

Rinse mouth.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. Personal protection: P1 filter respirator for inert particles.
Separated from strong oxidants, strong bases.

ICSC: 0379 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

ASCORBIC ACID

ICSC: 0379

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
ODOURLESS, WHITE TO SLIGHTLY YELLOW CRYSTALS OR POWDER

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance is a strong reducing agent and reacts with oxidants. The solution in water is a medium strong acid.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

INHALATION RISK:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates the eyes, the skin and the respiratory tract.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Melting point (decomposes): 190-192°C
Density: 1.65
g/cm3
Solubility in water, g/100 ml: 33
Octanol/water partition coefficient as log Pow: -2.15

ENVIRONMENTAL
DATA


N O T E S

ADDITIONAL INFORMATION



ICSC: 0379 ASCORBIC ACID
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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