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NIOSH

ISOBUTANOLAMINE

ICSC: 0285

2-Amino-2-methyl-1-propanol
2-Amino-2-methylpropanol
2-Aminoisobutanol
2-Aminodimethylethanol
C4H11NO / (CH3)2C(NH2)CH2OH
Molecular mass: 89.1
ICSC # 0285 		CAS # 124-68-5
RTECS # UA5950000
EC # 603-070-00-6
October 10, 2002 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Above 67°C explosive vapour/air mixtures may be formed.
Above 67°C use a closed system, ventilation.

EXPOSURE
STRICT HYGIENE! PREVENT GENERATION OF MISTS! PREVENT DISPERSION OF DUST!

•INHALATION Cough. Sore throat.
Local exhaust or breathing protection.
Fresh air, rest. Refer for medical attention.
•SKIN Redness. Pain.
Protective gloves.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
•EYES Redness. Pain. Severe deep burns.
Safety goggles, or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Abdominal pain. Burning sensation.
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Sweep spilled substance into covered containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: A/P2 filter respirator for organic vapour and harmful dust.)
Separated from strong oxidants, strong acids.

Xi symbol
R: 36/38-52/53
S: 2-61
ICSC: 0285 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

ISOBUTANOLAMINE

ICSC: 0285

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
CRYSTALS OR COLOURLESS LIQUID

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on burning producing toxic fumes including nitrogen oxides . The solution in water is a medium strong base. Reacts with strong acids , strong oxidants .

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: IIb (not established but data is available) (DFG 2005).


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is corrosive to the eyes. The substance is severely irritating to the skin . The aerosol is irritating to the respiratory tract .

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the liver when ingested.

PHYSICAL
PROPERTIES

Boiling point: 165°C
Melting point: 31°C
Density: 0.93
g/cm3
Solubility in water:
miscible
Vapour pressure, Pa at 20°C: 133
Relative vapour density (air = 1): 3.0
Flash point:
67°C c.c.

ENVIRONMENTAL
DATA


N O T E S

Health effects of exposure to the substance have not been investigated adequately.
NFPA Code: H2; F2; R0
Card has been partially updated in January 2008: see Ingestion First Aid.

ADDITIONAL INFORMATION



ICSC: 0285 ISOBUTANOLAMINE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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