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NIOSH

2-NITROPROPANE

ICSC: 0187

Isonitropropane
Dimethylnitromethane
sec-Nitropropane
2-NP
C3H7NO2 / CH3CHNO2CH3
Molecular mass: 89.1
ICSC # 0187 		CAS # 79-46-9
RTECS # TZ5250000
UN # 2608
EC # 609-002-00-1
April 04, 2006 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Above 24°C explosive vapour/air mixtures may be formed.
Above 24°C use a closed system, ventilation, and explosion-proof electrical equipment.
In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.
EXPOSURE
AVOID ALL CONTACT!

•INHALATION Cough. Dizziness. Drowsiness. Headache. Nausea. Vomiting. Diarrhoea. Weakness. Shortness of breath.
Ventilation, local exhaust, or breathing protection.
Refer for medical attention.
•SKIN Dry skin. Redness.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
•EYES Redness. Pain.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION (Further see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Remove all ignition sources. Evacuate danger area in case of a large spillage! Consult an expert! Personal protection: self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place.
Fireproof. Separated from strong bases, strong acids, amines , powdered metals , food and feedstuffs .

Note: E
T symbol
R: 45-10-20/22
S: 53-45
UN Hazard Class: 3
UN Packing Group: III
Signal: Danger
Excl mark-Health haz
Harmful if swallowed
Harmful if inhaled vapour
Suspected of causing genetic defects
May cause cancer
Causes damage to liver
ICSC: 0187 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

2-NITROPROPANE

ICSC: 0187

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D

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PHYSICAL STATE; APPEARANCE:
COLOURLESS , OILY LIQUID.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on burning producing toxic fumes including nitrogen oxides . Shock-sensitive compounds are formed with acids, amines, inorganic bases and heavy metal oxides. Attacks some forms of plastic rubber and coatings.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 10 ppm; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2005).
MAK: skin absorption (H);
Carcinogen category: 2
(DFG 2005).
OSHA PEL†: TWA 25 ppm (90 mg/m3)
NIOSH REL: Ca See Appendix A
NIOSH IDLH: Ca 100 ppm See: 79469


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The vapour of this substance is irritating to the eyes and the respiratory tract . The substance is mildly irritating to the skin . The substance may cause effects on the central nervous system . Exposure far above the OEL could cause liver impairment . Exposure far above the OEL may result in death.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The liquid defats the skin. This substance is possibly carcinogenic to humans.

PHYSICAL
PROPERTIES

Boiling point: 120°C
Melting point: -91°C
Relative density (water = 1): 0.99
Solubility in water, g/100 ml at 25°C: 1.7
Vapour pressure, kPa at 20°C: 1.7
Relative vapour density (air = 1): 3.1
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04
Flash point: 24°C c.c.
Auto-ignition temperature: 428°C
Explosive limits, vol% in air: 2.6-11
Octanol/water partition coefficient as log Pow: 0.93

ENVIRONMENTAL
DATA


N O T E S

Depending on the degree of exposure, periodic medical examination is suggested. The odour warning when the exposure limit value is exceeded is insufficient. NiPar S-20 and NiPar S-30 are trade names. Do NOT take working clothes home.
Transport Emergency Card: TEC (R)-30GF1-III
NFPA Code: H1; F3; R2

ADDITIONAL INFORMATION



ICSC: 0187 2-NITROPROPANE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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