Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content
NIOSH

ISOPROPYL GLYCIDYL ETHER

ICSC: 0171

1,2-Epoxy-3-isopropoxypropane
IGE
(Isopropoxymethyl)oxirane
C6H12O2
Molecular mass: 116.2
ICSC # 0171 		CAS # 4016-14-2
RTECS # TZ3500000
UN # 1993
November 25, 1998 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Flammable.
NO open flames, NO sparks, and NO smoking.
Powder, AFFF, foam, carbon dioxide.
EXPLOSION Above 33°C explosive vapour/air mixtures may be formed.
Above 33°C use a closed system, ventilation, and explosion-proof electrical equipment.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
PREVENT GENERATION OF MISTS!

•INHALATION Burning sensation. Cough. Dizziness. Headache. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Refer for medical attention.
•SKIN Redness. Pain.
Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
•EYES Redness. Pain.
Safety spectacles or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION
Do not eat, drink, or smoke during work.
Rinse mouth. Give plenty of water to drink.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Carefully collect remainder, then remove to safe place. Personal protection: filter respirator for organic gases and vapours.
Fireproof. Separated from strong oxidants, acids. Cool. Dry. Keep in the dark. Well closed.

UN Hazard Class: 3
UN Packing Group: III
ICSC: 0171 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

ISOPROPYL GLYCIDYL ETHER

ICSC: 0171

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance can presumably form explosive peroxides upon exposure to air or light. Reacts violently with strong oxidants amines and acids .

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 50 ppm as TWA, 75 ppm as STEL; (ACGIH 2004).
MAK:
Carcinogen category: 3B;
(DFG 2004).
OSHA PEL†: TWA 50 ppm (240 mg/m3)
NIOSH REL: C 50 ppm (240 mg/m3) 15-minute
NIOSH IDLH: 400 ppm See: 4016142


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes , the skin and the respiratory tract . Inhalation of vapour may cause lung oedema (see Notes). The substance may cause effects on the central nervous system. Exposure above the OEL could cause lowering of consciousness.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Boiling point: 137°C
Relative density (water = 1): 0.92
Solubility in water, g/100 ml: 19
Vapour pressure, kPa at 25°C: 1.25
Relative vapour density (air = 1): 4.15
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04
Flash point: 33°C c.c.
Explosive limits, vol% in air: see Notes
Octanol/water partition coefficient as log Pow: 0.5

ENVIRONMENTAL
DATA


N O T E S

Explosive limits are unknown in literature, although the substance is combustible and has a flash point < 61°C. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. Check for peroxides prior to distillation; eliminate if found. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response.
Transport Emergency Card: TEC (R)-30GF1-III

ADDITIONAL INFORMATION



ICSC: 0171 ISOPROPYL GLYCIDYL ETHER
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
Top