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Platinum (soluble salts, as Pt)

May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)

CAS number: Varies

NIOSH REL: 0.002 mg/m3 TWA

Current OSHA PEL: 0.002 mg/m3 TWA

1989 OSHA PEL: Same as current PEL

1993-1994 ACGIH TLV: 0.002 mg/m3 TWA

Description of substance: Varies

Original (SCP) IDLH*: No Evidence [*Note: "Effective" IDLH = 4 mg Pt/m3 -- see discussion below.]

Basis for original (SCP) IDLH: Air concentrations at or slightly above the OSHA PEL for soluble platinum salts can elicit an allergic response in sensitized workers. Therefore, the IDLH cannot be set to protect these sensitized individuals. The available toxicological data do not indicate any toxic effects in nonsensitized individuals. Because there is no evidence of an IDLH for nonsensitized individuals, for this draft technical standard, respirators have been selected on the basis of the assigned protection factor afforded by each device up to 2,000 ´ the OSHA PEL of 0.002 mg Pt/m3 (i.e., 4 mg Pt/m3); only the "most protective" respirators are permitted for use in concentrations exceeding 4 mg Pt/m3.

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Animal or human data: None relevant for use in determining the revised IDLH.

Revised IDLH: 4 mg Pt/m3

Basis for revised IDLH: Since the available toxicological data do not indicate any acute toxic effects in nonsensitized individuals, the revised IDLH for soluble platinum salts is 4 mg Pt/m3 based on being 2,000 times the NIOSH REL or OSHA PEL (2,000 is an assigned protection factor for respirators and was used during the Standards Completion Program for deciding when the "most protective" respirators should be used for soluble platinum salts). Since air concentrations of soluble platinum salts slightly above the NIOSH REL and OSHA PEL can elicit allergic responses in sensitized individuals, the revised IDLH cannot be set to protect these sensitized individuals.

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