Tellurium hexafluoride (as Te)

CAS number: 7783–80–4

NIOSH REL: 0.02 ppm (0.1 mg/m³) TWA

Current OSHA PEL: 0.02 ppm (0.2 mg/m³) TWA

1989 OSHA PEL: Same as current PEL

1993-1994 ACGIH TLV: 0.02 ppm (0.10 mg/m³) TWA

Description of substance: Colorless gas with a repulsive odor.

LEL :. . Nonflammable Gas

Original (SCP) IDLH: 1 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the statements by ACGIH [1971] that "animals showed evidence of pulmonary edema (disturbed breathing) at the lowest exposure tested, 1 ppm for 4 hours; a 1-hour exposure at 1 ppm produced greatly accelerated respiration but no mortality" [Kimmerle 1960]. The IDLH has been conservatively set, but no other data on acute inhalation toxicity are available on which to base an IDLH. Exposure for 4 hours to higher concentrations (5, 10, 25, 50, and 100 ppm) invariably proved fatal to all exposed animals [Kimmerle 1960].

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Lethal concentration data:

Species	Reference	LC50 (ppm)	LCLo (ppm)	Time	Adjusted 0.5-hr LC (CF)	Derived value
Rat Mouse Rabbit G. pig	Kimmerle 1960 Kimmerle 1960 Kimmerle 1960 Kimmerle 1960	----- ----- ----- -----	5 5 5 5	4 hr 1 hr 4 hr 4 hr	10 ppm (2.0) 6.3 ppm (1.25) 10 ppm (2.0) 10 ppm (2.0)	1.0 ppm 0.6 ppm 1.0 ppm 1.0 ppm

Other animal data: It has been reported that animals showed evidence of pulmonary edema (disturbed breathing) at the lowest exposure tested, 1 ppm for 4 hours; a 1-hour exposure at 1 ppm produced greatly accelerated respiration but no mortality [Kimmerle 1960].

Human data: None relevant for use in determining the revised IDLH.

Revised IDLH: 1 ppm [Unchanged] Basis for revised IDLH: Based on acute inhalation toxicity data in animals [Kimmerle 1960], the original IDLH for tellurium hexafluoride (1 ppm) is not being revised at this time.

REFERENCES:

1. ACGIH [1971]. Tellurium hexafluoride. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 246.

2. Kimmerle G [1960]. Vergleichende untersuchungen der inhalationstoxicitat von schwefel-, selen- und tellurhexafluorid. Arch Toxikol 18:140-144 (in German).