Methamphetamines - Method 9109

Proposed NIOSH 9109 for Methamphetamine and Illicit Drugs, Precursors, and Adulterants on Wipes by Solid Phase Extraction Gas Chromatography-Mass Spectrometry (GC/MS) is a sampling and analytical method that will be included in the NIOSH Manual of Analytical Methods, 5th edition. Two other proposed methamphetamine wipe methods will also be included. NIOSH 9106 is a Liquid-Liquid Extraction Gas Chromatography-Mass Spectrometry (GC/MS) method and NIOSH 9111 is a Liquid Chromatography-Mass Spectrometry (LC/MS) method. NIOSH 9109 has a quicker sample preparation time to run a larger number of samples, but has more problems with interferences than NIOSH 9106. NIOSH 9111 is quickest and least expensive of the three methods, but has only been evaluated for the measurement of methamphetamine and not other illicit drugs of interest.

Material Under Consideration

NIOSH Final document: Methamphetamine and Illicit Drugs, Precursors, and Adulterants on Wipes by Solid Phase Extraction; NIOSH Method 9109 -- 10/17/11 [PDF - 27,606 KB]

Draft NIOSH document; (NIOSH Manual of Analytical Methods (NMAM), Fifth Edition; Methamphetamine and Illicit Drugs, Precursors, and Adulterants on Wipes by Solid Phase Extraction); 1/1/09 [PDF - 28,686 KB]

Draft NIOSH document; (Methamphetamine and Illicit Drugs, Precursors, and Adulterants on Wipes by Solid Phase Extraction); 9/20/09 [PDF - 63,722 KB]

Submissions in order of Receipt

NIOSH responses to external review comments – 6/1/11 [PDF - 16,209 KB]

Submission to the docket from Groff (Research Chemist) –3/31/08 [PDF - 1,049 KB]

Submission to the docket from external reviewer (1) – 10/1/09 [PDF - 1,633 KB]

Reference (1); Martyny JW (2008). Variability in the Analysis of Wipe Samples Taken for Methamphetamine Contamination; 3/19/08 [PDF - 23,978 KB]

Reference (2); Martyny JW (2008). Methamphetamine Sampling Variability on Different Surfaces using Different Solvents; 10/1/08 [PDF - 14,579 KB]

Reference (3); Martyny JW (2008). Decontamination of Building Materials Contaminated with Methamphetamine; 1/1/08 [PDF - 13,973 KB]

Submission to the docket from external reviewer (2) – 10/1/09 [PDF - 961 KB]

Submission to the docket from external reviewer (3) – 10/1/09 [PDF - 554 KB]

Submission to the docket from external reviewer (4) – 10/1/09 [PDF - 5,456 KB]

Submission to the docket from external reviewer (5) – 10/1/09 [PDF - 1,728 KB]