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Issue 10, March 11, 2013

This week's featured articles lead off with a literature review by A Penman-Aguilar et al focused on economic disadvantage as a key factor in teen childbearing; this article is part of a Public Health Reports supplement on sexual health. Another maternal and child health related review by J Rosenthal and colleagues finds significant declines in neural tube defect prevalence in Latin America, with greater declines seen where folic acid fortification achieved population penetrance.

Safety of food along the "farm to table" continuum occupies two slots among the weekly features. A group of CDC authors led by F Medalla finds increased resistance or nonsusceptibility of Salmonella strains to multiple broad spectrum antibiotics, despite declining multidrug resistance. At the "table" end of the spectrum, ME Kendall and collaborators document the emergence of salsa and guacamole as important vehicles of foodborne disease outbreaks over the past thirty-five years.

Vaccinologists might speak of the "bench to bedside" continuum, as noted in a pair of articles this week. JA Belser and TM Tumpey summarize what has been learned from the use of mouse and ferret models to study highly pathogenic H5N1 influenza. Writing in Pediatrics, PA Gastanaduy and collaborators note sustained declines in diarrheal disease deaths among children in all regions of Mexico following introduction of rotavirus vaccine.

Potential high-impact articles involving the global "big three" disease (HIV, malaria, and TB) complete this week's top ten. In PLoS One, a group led by JC Chehab note progress in TB and HIV program integration in South Africa, along with remaining gaps in clinical care. Also published in PLoS One is an analysis first-authored by DB Nguyen, which favorably evaluates implementation of antiretroviral therapy in Vietnam. Switching to malaria, a systematic review and meta-analysis led by K Kayentao and published in JAMA finds that preventive therapy with 3 or more doses of sulfadoxine-pyrimethamine had beneficial effects on infants compared to standard 2 dose regimens. A non-clinical malaria intervention (indoor residual spraying) is shown by LC Steinhardt et al to result in lower risk of parasitemia and anemia, in a study conducted in northern Uganda.

John Iskander
Editor, Science Clips


  1. Top Ten Articles of the Week
    Selected weekly by a senior CDC scientist from the standard sections listed below.
  2. CDC Authored Publications
    The names of CDC authors are indicated in bold text.
    Articles published in the past 6-8 weeks authored by CDC or ATSDR staff.
  3. Public Health Articles Noted in the Media
    Articles about important public health topics that have been mentioned in the press.

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CDC Science Clips Production Staff

John Iskander, MD MPH,

Editor Rebecca Satterthwaite, MS,

Librarian Gail Bang, MLIS,

Librarian Deidre Thomas, MLS,

Librarian Kathleen Connick, MSLS,

Librarian Barbara Landreth, MLS,

Librarian Joseph Dunlap,

Web Developer Joe Bryce, Web Developer

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DISCLAIMER: Articles listed in the CDC Science Clips are selected by the Stephen B. Thacker CDC Library to provide current awareness of the public health literature. An article's inclusion does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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