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Case Studies

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Ethylene Glycol and Propylene Glycol Toxicity
How to Use This Course

Course: WB 1103
CE Original Date: October 3, 2007
CE Renewal Date: October 3, 2010
CE Expiration Date: October 3, 2012
Download Printer-Friendly version [PDF - 496 KB]

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Introduction

The goal of Case Studies in Environmental Medicine (CSEM) is to increase the primary care provider's knowledge of hazardous substances in the environment and to help in evaluation and treating of potentially exposed patients. This CSEM focuses on ethylene glycol and propylene glycol toxicity.

Available Versions

Two versions of the Ethylene Glycol and Propylene Glycol Toxicity. CSEM are available

the HTML version http://www.atsdr.cdc.gov/csem/csem.asp?csem=12&po=0 provides content through the Internet;
the downloadable PDF [496 KB] version provides content in an electronic, printable format, especially for those who may lack adequate Internet service.
The HTML version offers interactive exercises and prescriptive feedback to the user.

Instructions

To make the most effective use of this course, we recommend that you

take the Initial Check to assess your current knowledge about ethylene glycol and propylene glycol toxicity
read the title, learning objectives, text, and key points in each section
complete the progress check exercises at the end of each section and check your answers
complete and submit your assessment and posttest response online if you wish to obtain continuing education credit. Continuing education certificates can be printed immediately upon completion.

Instructional Format

This course is designed to help you learn efficiently. Topics are clearly labeled so that you can skip sections or quickly scan sections you are already familiar with. This labeling will also allow you to use this training material as a handy reference. To help you identify and absorb important content quickly, each section is structured as follows

Section Element	Purpose
Title	Serves as a “focus question” that you should be able to answer after completing the section
Learning Objectives	Describes specific content addressed in each section and focuses your attention on important points
Text	Provides the information you need to answer the focus question(s) and achieve the learning objectives
Key Points	Highlights important issues and helps you review
Progress Check exercises	Enables you to test yourself to determine whether you have mastered the learning objectives
Progress Check answers	Provides feedback to ensure you understand the content and can locate information in the text

Learning Objectives

Upon completion of the Ethylene Glycol and Propylene Glycol Toxicity CSEM, you will be able to

Topic	Objectives
What is ethylene glycol?	Describe the properties of ethylene glycol
Where is ethylene glycol found?	Identify sources of ethylene glycol exposure
How are people exposed to ethylene glycol?	Identify the primary route of exposure to ethylene glycol
What Are the U.S. Standards for ethylene glycol exposure levels?	Identify the American Conference of Governmental Industrial Hygienists (ACGIH) ceiling exposure limit for ethylene glycol Identify the U.S. Environmental Protection Agency's (EPA) guidelines for ethylene glycol in drinking water
What is the biologic fate of ethylene glycol?	Describe why individuals with impaired liver function are more likely to suffer less toxicity but greater intensity of the initial central nervous system (CNS) effects caused by ethylene glycol exposure
What are the stages of ethylene glycol intoxication?	Explain the mechanism of ethylene glycol toxicity Describe the three stages of ethylene glycol toxicity
What are the physiologic effects of ethylene glycol poisoning?	Describe the physiologic effects of ethylene glycol poisoning
How should patients exposed to ethylene glycol be evaluated?	Describe the primary focus of the exposure history Describe how the actual clinical presentation changes over time as intoxication evolves
What laboratory tests can help in evaluating patients exposed to ethylene glycol?	Identify the abnormal laboratory findings associated with ethylene glycol poisoning. List three measurements that can assist with diagnosis of ethylene glycol poisoning
How should patients exposed to ethylene glycol be treated?	Identify the primary treatment strategy for managing ethylene glycol poisoning case
What is propylene glycol?	Describe the properties and uses of propylene glycol
What instructions should be given to patients?	Explain advice on self care and follow-up care to patients who are exposed to ethylene glycol or propylene glycol