Macrophage theory of depression

The macrophage theory of depression, also known as the inflammatory theory of depression, is the theory that depression may be the result of macrophage activity as part of the process of inflammation.[1] The theory is the subject of ongoing research.[2][3][4]

References

Abbott, Alison (2018-05-29). "Depression: the radical theory linking it to inflammation". Nature. 557 (7707): 633–634. Bibcode:2018Natur.557..633A. doi:10.1038/d41586-018-05261-3.
Kopschina Feltes P, Doorduin J, Klein HC, Juárez-Orozco LE, Dierckx RA, Moriguchi-Jeckel CM, de Vries EF (September 2017). "Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy". Journal of Psychopharmacology. 31 (9): 1149–1165. doi:10.1177/0269881117711708. PMC 5606303. PMID 28653857.
Dey A, Hankey Giblin PA (June 2018). "Insights into Macrophage Heterogeneity and Cytokine-Induced Neuroinflammation in Major Depressive Disorder". Pharmaceuticals. 11 (3): 64. doi:10.3390/ph11030064. PMC 6160985. PMID 29941796.
Gałecki P, Talarowska M (June 2018). "Inflammatory theory of depression". Psychiatria Polska. 52 (3): 437–447. doi:10.12740/PP/76863. PMID 30218560.

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[1] Abbott, Alison (2018-05-29). "Depression: the radical theory linking it to inflammation". Nature. 557 (7707): 633–634. Bibcode:2018Natur.557..633A. doi:10.1038/d41586-018-05261-3.

[2] Kopschina Feltes P, Doorduin J, Klein HC, Juárez-Orozco LE, Dierckx RA, Moriguchi-Jeckel CM, de Vries EF (September 2017). "Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy". Journal of Psychopharmacology. 31 (9): 1149–1165. doi:10.1177/0269881117711708. PMC 5606303. PMID 28653857.

[3] Dey A, Hankey Giblin PA (June 2018). "Insights into Macrophage Heterogeneity and Cytokine-Induced Neuroinflammation in Major Depressive Disorder". Pharmaceuticals. 11 (3): 64. doi:10.3390/ph11030064. PMC 6160985. PMID 29941796.

[4] Gałecki P, Talarowska M (June 2018). "Inflammatory theory of depression". Psychiatria Polska. 52 (3): 437–447. doi:10.12740/PP/76863. PMID 30218560.