Eupatilin

Eupatilin
Clinical data
Dependence; liability	None
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	CA: not available ; UK: not available ; US: not available ; In general: ℞ (Prescription only);
Identifiers
	IUPAC name 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one;
CAS Number	22368-21-4 ;
PubChem CID	5273755;
ChemSpider	4438134 ;
CompTox Dashboard (EPA)	DTXSID30176904 ;
Chemical and physical data
Formula	C18H16O7
Molar mass	344.315 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C\1c3c(O)c(OC)c(O)cc3O/C(=C/1)c2ccc(OC)c(OC)c2;
	InChI InChI=1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3 ; Key:DRRWBCNQOKKKOL-UHFFFAOYSA-N ;
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Eupatilin (5,7-Dihydroxy-3',4',6-trimethoxyflavone) is an O-methylated flavone, a type of flavonoids. It can be found in Artemisia asiatica (Asteraceae).[1]

References

Kim, D. H.; Na, H. K.; Oh, T. Y.; Kim, W. B.; Surh, Y. J. (2004). "Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces cell cycle arrest in ras-transformed human mammary epithelial cells". Biochemical Pharmacology. 68 (6): 1081–1087. doi:10.1016/j.bcp.2004.04.027. PMID 15313404.

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[1] Kim, D. H.; Na, H. K.; Oh, T. Y.; Kim, W. B.; Surh, Y. J. (2004). "Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces cell cycle arrest in ras-transformed human mammary epithelial cells". Biochemical Pharmacology. 68 (6): 1081–1087. doi:10.1016/j.bcp.2004.04.027. PMID 15313404.