Difference between revisions of "Oxalic acid"

From WikEM
Jump to: navigation, search
(Created page with "==Background== *Used in bleach and rust removers *Also found in some species of plants ==Mechanism of Toxicity== *Solution form: **Irritative and Corrosive **Causes hypocalce...")
 
 
Line 33: Line 33:
 
*Olson, K. Poisoning and Drug Overdose, 1999.
 
*Olson, K. Poisoning and Drug Overdose, 1999.
 
<references/>
 
<references/>
 +
 +
[[Category:Toxicology]]

Latest revision as of 03:55, 7 May 2017

Background

  • Used in bleach and rust removers
  • Also found in some species of plants

Mechanism of Toxicity

  • Solution form:
    • Irritative and Corrosive
    • Causes hypocalcemia and formation of calcium oxalate crystals that can deposit in brain, heart, and kidneys.
  • Insoluble form:
    • Local mucous membrane irritation

Toxic Dose

  • 5-15 g can be lethal

Clinical Features

  • Direct contact with skin/eyes
    • Skin and eye irritation and burning
  • Inhalation
    • Sore throat, cough, wheezing, pulmonary edema
  • Ingestion
    • Weakness, tetany, cardiac arrest

Diagnosis

  • Clinical
  • No specific levels for oxalic acid

Management

  • Protect the airway
  • Decontamination
  • Calcium chloride or calcium gluconate to reverse hypocalcemia

References

  • Olson, K. Poisoning and Drug Overdose, 1999.