Zofenoprilat

Zofenoprilat
Names
	IUPAC name (2S,4S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]-4-(phenylsulfanyl)pyrrolidine-2-carboxylic acid
Identifiers
CAS Number	75176-37-3;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:82602;
ChEMBL	ChEMBL16332;
ChemSpider	24540938;
DrugBank	DB08766;
PubChem CID	3034048;
UNII	4G4WDK2YBS;
CompTox Dashboard (EPA)	DTXSID50231443 ;
	InChI InChI=1S/C15H19NO3S2/c1-10(9-20)14(17)16-8-12(7-13(16)15(18)19)21-11-5-3-2-4-6-11/h2-6,10,12-13,20H,7-9H2,1H3,(H,18,19)/t10-,12-,13-/m0/s1 Key: UQWLOWFDKAFKAP-DRZSPHRISA-N; InChI=1/C15H19NO3S2/c1-10(9-20)14(17)16-8-12(7-13(16)15(18)19)21-11-5-3-2-4-6-11/h2-6,10,12-13,20H,7-9H2,1H3,(H,18,19)/t10-,12-,13-/m0/s1 Key: UQWLOWFDKAFKAP-DRZSPHRIBV;
	SMILES C[C@H](CS)C(=O)N1C[C@H](C[C@H]1C(O)=O)SC1=CC=CC=C1;
Properties
Chemical formula	C15H19NO3S2
Molar mass	325.44 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Zofenoprilat is an angiotensin-converting enzyme inhibitor and is the free sulfhydryl active metabolite of zofenopril.[1]

References

Subissi, A; Evangelista, S; Giachetti, A (1999). "Preclinical Profile of Zofenopril: An Angiotensin Converting Enzyme Inhibitor with Peculiar Cardioprotective Properties". Cardiovascular Drug Reviews. 17 (2): 115. doi:10.1111/j.1527-3466.1999.tb00008.x.

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Angiotensin receptor modulators
ATR	Agonists: Angiotensin II Angiotensin III Angiotensin IV Saralasin Antagonists: Abitesartan Azilsartan Candesartan Elisartan Embusartan Eprosartan EXP-3174 Fimasartan Forasartan Irbesartan Losartan Milfasartan Olmesartan Olodanrigan PD123319 Pomisartan Pratosartan Ripisartan Saprisartan Sparsentan Tasosartan Telmisartan Valsartan Zolasartan ACE inhibitors: Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril Lisinopril Moexipril Omapatrilat Perindopril Quinapril Quinaprilat Ramipril Rentiapril Rescinnamine Spirapril Spiraprilat Temocapril Trandolapril Zofenopril Zofenoprilat Renin inhibitors: Aliskiren Ciprokiren Ditekiren Enalkiren Imarikiren Pepstatin Remikiren Terlakiren Zankiren Propeptides: Angiotensinogen Angiotensin I
Combinations:	Valsartan/hydrochlorothiazide Valsartan/hydrochlorothiazide/amlodipine Amlodipine/valsartan
See also Receptor/signaling modulators Signaling peptide/protein receptor modulators