Wolf's isotopic response

Wolf's isotopic response[1][2] is a dermatological sign that is characterized by the appearance of a new dermatosis or cutaneous infection at the site of a previous unrelated and already healed dermatosis ("isotopic" means identical location).[3][4]


  1. Shemer A, Weiss G, Trau H (September 2001). "Wolf's isotopic response: a case of zosteriform lichen planus on the site of healed herpes zoster". J Eur Acad Dermatol Venereol. 15 (5): 445–7. doi:10.1046/j.1468-3083.2001.00345.x. PMID 11763387.
  2. Fernández-Redondo V, Amrouni B, Varela E, Toribio J (November 2002). "Granulomatous folliculitis at sites of herpes zoster scars: Wolf's isotopic response". J Eur Acad Dermatol Venereol. 16 (6): 628–30. doi:10.1046/j.1468-3083.2002.00524.x. PMID 12482051.
  3. Wolf R, Wolf D, Ruocco E, Brunetti G, Ruocco V (2011). "Wolf's isotopic response". Clin. Dermatol. 29 (2): 237–40. doi:10.1016/j.clindermatol.2010.09.015. PMID 21396564.
  4. Wolf R, Brenner S, Ruocco V, Filioli FG (May 1995). "Isotopic response". Int. J. Dermatol. 34 (5): 341–8. doi:10.1111/j.1365-4362.1995.tb03616.x. PMID 7607796.

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