Visnadine

Visnadine
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	C04AX24 (WHO) ;
Identifiers
	IUPAC name (9R,10R)-10-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2R)-2-methylbutanoate;
CAS Number	477-32-7;
PubChem CID	442151;
ChemSpider	390669;
UNII	0RL4V0K263;
KEGG	D08735 ;
ECHA InfoCard	100.006.833
Chemical and physical data
Formula	C21H24O7
Molar mass	388.41 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC[C@H](C(=O)O[C@H]1[C@@](OC2=C([C@H]1OC(=O)C)C3=C(C=CC(=O)O3)C=C2)(C)C)C;
	InChI InChI=1S/C21H24O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h7-11,18-19H,6H2,1-5H3/t11-,18-,19-/m1/s1; Key:GVBNSPFBYXGREE-CXWAGAITSA-N;
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Visnadine (or visnadin) is a natural vasodilator.[1] It was first isolated from bishop's weed (Ammi visnaga), a plant indigenous to the Mediterranean region which has been used for centuries in Egypt as a spasmolytic.[2]

References

Durate, J; Vallejo I; Pérez-Vizcaino F; Jiménez R; Zarzuelo A; Tamargo J (1997). "Effects of visnadine on rat isolated vascular smooth muscles.". Planta Med. Thieme Medical Publishers. 63 (3): 233–6. doi:10.1055/s-2006-957660. ISSN 1439-0221. PMID 9225605.
Eric Smith; Norman Hosansky; W. G. Bywater & Eugene E. van Tamelen (1957). "Constitution of Samidin, Dihydrosamidin and Visnadin". J. Am. Chem. Soc. 79 (13): 3534–3540. doi:10.1021/ja01570a062.

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[1] Durate, J; Vallejo I; Pérez-Vizcaino F; Jiménez R; Zarzuelo A; Tamargo J (1997). "Effects of visnadine on rat isolated vascular smooth muscles.". Planta Med. Thieme Medical Publishers. 63 (3): 233–6. doi:10.1055/s-2006-957660. ISSN 1439-0221. PMID 9225605.

[2] Eric Smith; Norman Hosansky; W. G. Bywater & Eugene E. van Tamelen (1957). "Constitution of Samidin, Dihydrosamidin and Visnadin". J. Am. Chem. Soc. 79 (13): 3534–3540. doi:10.1021/ja01570a062.

Peripheral vasodilators (C04)
Phenylethanolamine derivatives	Isoxsuprine Buphenine Bamethan
Alpha blockers	Non-selective Tolazoline Phentolamine Selective α₁-blockers Alfuzosin Doxazosin Prazosin Silodosin Tamsulosin Terazosin
Niacin and derivatives	Niacin Nicotinyl alcohol Inositol nicotinate Ciclonicate
Purine derivatives	Pentifylline Xantinol nicotinate Pentoxifylline Etofylline nicotinate
Ergot alkaloids	Ergoloid Nicergoline Dihydroergocristine
Other peripheral vasodilators	Cyclandelate Phenoxybenzamine Vincamine Moxisylyte Bencyclane Vinburnine Sulcotidil Buflomedil Naftidrofuryl Butalamine Visnadine Cetiedil Cinepazide Ifenprodil Azapetine Fasudil