Menthyl isovalerate
Menthyl isovalerate, also known as validolum, is the menthyl ester of isovaleric acid. It is a transparent oily, colorless liquid with a smell of menthol. It is very slightly soluble in ethanol, while practically insoluble in water. It is used as a food additive for flavor and fragrance.[1]
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| Names | |
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| IUPAC name
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 3-methylbutanoate | |
| Other names
Validolum; Valofin; Validol; Menthoval | |
| Identifiers | |
CAS Number |
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3D model (JSmol) |
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| ChemSpider | |
| ECHA InfoCard | 100.036.766 |
PubChem CID |
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| Properties | |
Chemical formula |
C15H28O2 |
| Molar mass | 240.387 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Medical use
In the former Soviet Union states including Russia, menthyl isovalerate is sold as an anxiolytic under various trade names including Validol, Valofin, and Menthoval.[2][3][4]
See also
- Methyl pentanoate
- Hopantenic acid
References
- Menthyl isovalerate
- Russian Medications List and Possible Side Effects
- Farmak Product Information - Validol
- Bondarenko IP, Liashenko MM, Chirkov SN, Ermakovich II (1996). "A comparative evaluation of the antianginal action of commercially and noncommercially produced validol in neurocirculatory dystonia and stenocardia". Lik Sprava. Mar-Apr (3–4): 110–113. PMID 9035841.
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