Surgical Outcomes Analysis and Research

Surgical Outcomes Analysis & Research, SOAR, is a research laboratory of the Department of Surgery at the Beth Israel Deaconess Medical Center with expertise in outcomes research. SOAR investigates surgical diseases and perioperative outcomes. The group focuses on pancreatic cancer, other gastrointestinal and hepatobiliary malignancies, vascular disease, and transplant surgery. SOAR's goal is to examine quality, delivery, and financing of care in order to have an immediate impact on patient care and system improvements. The group members utilize national health services and administrative databases, as well as institutional databases, to investigate and to address factors contributing to disease outcomes and healthcare disparities.

Surgical Outcomes Analysis & Research (SOAR)
Type
Research
FoundedWorcester, MA, 2007
FounderJennifer F. Tseng, MD, MPH
Headquarters
Boston, MA
,
United States
Key people
James R. Rodrigue, PhD
(Co-Director)
Marc L. Schermerhorn, MD
(Co-Director)
Jennifer F. Tseng, MD, MPH
(Co-Director)
WebsiteSOAR Website

The work in SOAR incorporates advanced statistical techniques, including logistic regression, prediction score, and decision analysis modeling.

About Outcomes Research

Outcomes Research evaluates the impact of health care on the health outcomes of patients and populations (see AHRQ for further details). This research may also include the evaluation of economic impacts linked to health outcomes, such as cost effectiveness and cost utility. An emphasis is placed on disease-oriented evaluations of care delivered in general, real-world settings. There are a wide range of outcomes to study including mortality, morbidity, functional status, mental well-being, and other aspects of health-related quality of life. Outcomes research is a multidisciplinary field of inquiry that examines the use, quality, delivery, and financing of health care services to increase knowledge and understanding of the structure, processes, and effects of health services for individuals and populations. Outcomes research provides the data to help solve critical problems that are faced in everyday clinical practice. The information learned can have an immediate impact on patient care and system improvement.

About SOAR

SOAR was founded in 2007 and relocated to Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA in 2012.

The mission of SOAR is to decrease perioperative morbidity and mortality, address health care disparities, and increase overall patient survival and quality of life. SOAR members hope, as part of the surgical outcomes research community, to improve overall outcomes for patients with surgical diseases.

Research Goals

  • Pancreatic cancer and pancreatic disease
  • Other gastrointestinal and hepatobiliary malignancies
  • Vascular disease
  • Transplant surgery and transplant psychology
  • Investigating factors that affect surgical outcomes for diverse specialties including colorectal, cardiovascular, transplant, plastic and reconstructive, and minimally invasive surgery

About Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts is a teaching hospital of Harvard Medical School. It was formed out of the 1996 merger of Beth Israel Hospital (founded in 1916) and New England Deaconess Hospital (founded in 1896).

See also: Beth Israel Deaconess Medical Center website

Ongoing Research

SOAR researchers use national health services and administrative databases as well as prospective institutional tissue-linked databases to investigate factors contributing to disease outcomes for pancreatic cancer, hepato biliary disease, vascular disease, colorectal disease, plastic and reconstructive surgery, and transplant medicine. These projects are under development with the use of the following databases:

Additionally, individual research groups have access to and have expertise in disease- and specialty-specific databases. These include:

  • Vascular Study Group of New England (VSGNE), a regional vascular surgery database.
  • Vascular Quality Initiative (VQI), a national vascular surgery database.
  • American Society of Thoracic Surgery (ASTS) database
  • National Trauma Data Bank (NTDB)
  • Scientific Registry of Transplant Recipients

Also, SOAR researchers are conducting patient-centered outcomes research designed to:

  • Measure health-related, functional, and other outcomes from the perspective of patients and their families
  • Develop decision aid tools and strategies to assist patients in making complex choices about their healthcare
  • Compare the effectiveness of surgical interventions on patient-reported outcomes

Personnel

  • James R. Rodrigue, PhD - SOAR Co-Director; Director, Behavioral Health Services and Research, The Transplant Center, Beth Israel Deaconess Medical Center; Professor, Psychiatry, Harvard Medical School
  • Marc L. Schermerhorn, MD - SOAR Co-Director; Chief, Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center; Associate Professor, Harvard Medical School
  • Jennifer F. Tseng, MD, MPH - SOAR Co-Director; Chief, Surgical Oncology, Beth Israel Deaconess Medical Center; Associate Professor, Surgery, Harvard Medical School

Fellows

  • James McPhee, MD - 2005- 2007 Research Fellow
  • Joshua Hill, MD - 2006- 2007 Research Fellow
  • Melissa Murphy, MD, MPH - 2007- 2009 Evans Pancreatic Cancer Research Fellow
  • Jessica Simons, MD - 2007- 2009 Karen Sweeney Polkinghorn Pancreatic Cancer Research Fellow
  • James Carroll, MD - 2008- 2010 Linda J. Verville Research Fellow
  • Jillian Smith, MD, MPH - 2009- 2011 William D. Maney Research Fellow
  • Andrew Burr, DO - 2009- 2011 Research Fellow
  • Elizaveta Ragulin Coyne, MD - 2010-2012 Linda J Verville Research Fellow
  • Elan Witkowski, MD - 2010-2012 Research Fellow
  • Ruby Lo, MD - 2010-2012 Research Fellow
  • Rodney Bensley, MD 2010-2012 Research Fellow
  • Zeling Chau, MD, MPH - 2011-2013 Research Fellow
  • Thomas Curran, MD - 2012-2014 Research Fellow
  • Tanya Vishnevsky, PhD - 2013-2014 Research Fellow
  • Dominique Buck, MD - 2013-2015 Research Fellow
  • John "Jack" McCallum, MD, MPH - 2013-2015 Research Fellow
  • Lindsay Bliss, MD, MPH - 2013-2015 Research Fellow
  • Catherine Yang, MBChB, MPH - 2013-2014 Research Fellow
  • Mariam Eskander, MD - 2014-2016 Research Fellow
  • Peter Soden, MD - 2014-2016 Research Fellow
  • Sara Zetterval, MD - 2014-2016 "Research fellow"

Team Members

  • Jodi-Ann Dattadeen - Transplant Surgery
  • Aaron Fleishman - Transplant Surgery
  • Alexa Hiley - Transplant Surgery
  • Maeve Moore - Transplant Surgery
  • Sucheta Ravindran - Transplant Surgery
  • Emily Schapira - Harvard Medical School Student
  • Sing Chau Ng, MS - Biostatistician
  • Jeremy Darling, BA - Research assistant, Vascular Surgery
  • Susanna de Geus - Postdoctoral Research Fellow
  • Kurt Schultz - University of Massachusetts Medical School Student

Former Personnel

  • Giles Whalen, MD - Surgical Oncology
  • Ted McDade, MD - Post-doctoral Research Scientist
  • Shimul Shah, MD - Transplant Surgery
  • Karim Alavi, MD - Colorectal Surgery
  • Heena Santry, MD - Trauma Surgery
  • (Frank) Zheng Zhou, MD, PhD - Consultant
  • Mary Sullivan, NP - Clinical Trials and Database Management
  • Mary Beth Curnen - Research Coordinator
  • Andreea Bodnari - Computer Science Assistant
  • Elisabet Manasanch, MD - Oncology

Former Team Members

  • Ed Arous - UMass Medical School Student
  • Erin Cooley, MD - UMass Surgical Resident
  • Charles Psoinos - UMass Medical School Student
  • Maia Sharuk - UMass Medical School Student
  • Josh Shaw - UMass Medical School Student
  • Jason Wiseman - UMass Medical School Student
  • Stephen Skinner - UMass Medical School Student
  • Nikki Burish - University of Wisconsin School of Medicine Student
  • Osman Yousafzai - King Edward Medical University Student

Publications

Publications 2014

Publications 2013

  • Arous, Edward J., et al. "Electronic medical record: research tool for pancreatic cancer?." Journal of Surgical Research (2013).
  • Bayliss George P, et al. (2013). "Immunosuppression after renal allograft failure: a survey of US practices". Clinical Transplantation. 27 (6): 895–900. doi:10.1111/ctr.12254. PMID 24118389.
  • Bensley, Rodney P., et al. "Accuracy of administrative data versus clinical data to evaluate carotid endarterectomy and carotid stenting." Journal of Vascular Surgery (2013).
  • Bensley, Rodney P., et al. "Risk of late-onset adhesions and incisional hernia repairs after surgery." Journal of the American College of Surgeons (2013).
  • Bensley, Rodney P., et al. "Open repair of intact thoracoabdominal aortic aneurysms in the American College of Surgeons National Surgical Quality Improvement Program." Journal of Vascular Surgery (2013).
  • Buck Dominique B., et al. "Endovascular treatment of abdominal aortic aneurysms." National Review of Cardiology (2013).
  • Chau, Zeling, et al. "Rankings versus reality in pancreatic cancer surgery: a real‐world comparison." HPB (2013).
  • Edwards, Samuel T., et al. "Comparative effectiveness of endovascular versus open repair of ruptured abdominal aortic aneurysm in the Medicare population." Journal of Vascular Surgery (2013).
  • Fokkema, M., et al. "Clinical Relevance of Cranial Nerve Injury following Carotid Endarterectomy." European Journal of Vascular and Endovascular Surgery (2013).
  • Fokkema, Margriet, et al. "In-hospital vs postdischarge adverse events following carotid endarterectomy." Journal of Vascular Surgery (2013).
  • Fokkema, Margriet, et al. "Selective external endarterectomy in patients with ipsilateral symptomatic internal carotid artery occlusion." Journal of Vascular Surgery (2013).
  • Glaser JD; et al. (2013). "Fate of the contralateral limb after lower extremity amputation". Journal of Vascular Surgery. 58 (6): 1571–1577. doi:10.1016/j.jvs.2013.06.055. PMC 3844063. PMID 23921246.
  • Kalish, Brian T., et al. "Quality Assessment in Pancreatic Surgery: What Might Tomorrow Require?." Journal of Gastrointestinal Surgery' 17.1 (2013): 86-93.
  • Khoynezhad A., et al. "Results of a multicenter, prospective trial of thoracic endovascular aortic repair for blunt thoracic aortic injury (RESCUE trial)." Journal of Vascular Surgery (2013).
  • Lo, Ruby C., et al. "Gender differences in abdominal aortic aneurysm presentation, repair, and mortality in the Vascular Study Group of New England." Journal of Vascular Surgery (2013).
  • Lo, Ruby C., et al. "Outcomes following infrapopliteal angioplasty for critical limb ischemia." Journal of Vascular Surgery (2013).
  • Lo, Ruby C., et al. "Presentation, treatment, and outcome differences between men and women undergoing revascularization or amputation for lower extremity peripheral arterial disease." Journal of Vascular Surgery (2013).
  • Lo Ruby C., et al. "Relative importance of aneurysm diameter and body size for predicting abdominal aortic aneurysm rupture in men and women." Journal of Vascular Surgery (2013).
  • Ragulin-Coyne E; et al. (2013). "Is Routine Intraoperative Cholangiogram Necessary in the Twenty-First Century? A National View". Journal of Gastrointestinal Surgery. 17 (3): 434–442. doi:10.1007/s11605-012-2119-8. PMC 4570242. PMID 23292460.
  • Ragulin‐Coyne, Elizaveta, et al. "National trends in pancreaticoduodenal trauma: interventions and outcomes." HPB (2013).
  • Rodrigue JR, Hanto DW, Curry MP (2013). "Substance abuse treatment and its association with relapse to alcohol use after liver transplantation". Liver Transplantation. 19 (12): 1387–1395. doi:10.1002/lt.23747. PMID 24123780.CS1 maint: multiple names: authors list (link)
  • Rodrigue JR, Hanto DW, Curry MP (2013). "The Alcohol Relapse Risk Assessment: a scoring system to predict the risk of relapse to any alcohol use after liver transplant". Progress in Transplantation. 23 (4): 310–318. doi:10.7182/pit2013604. PMID 24311394.CS1 maint: multiple names: authors list (link)
  • Rodrigue JR; et al. (2013). "Patient-reported immunosuppression nonadherence 6 to 24 months after liver transplant: association with pretransplant psychosocial factors and perceptions of health status change". Progress in Transplantation. 23 (4): 319–328. doi:10.7182/pit2013501. PMC 4127806. PMID 24311395.
  • Rodrigue, James R., et al. "Trajectories of Perceived Benefits in Living Kidney Donors: Association With Donor Characteristics and Recipient Outcomes." Transplantation (2013).
  • Rodrigue JR; et al. (2013). "Willingness to Pursue Live-Donor Kidney Transplantation Among Waitlisted Patients Infected With Human Immunodeficiency Virus (HIV): A Preliminary Investigation". Transplantation. 95 (6): 787–790. doi:10.1097/tp.0b013e318282f282. PMC 3604048. PMID 23388735.
  • Rodrigue, James R., Jesse D. Schold, and Didier A. Mandelbrot. "The Decline in Living Kidney Donation in the United States: Random Variation or Cause for Concern?." Transplantation (2013).
  • Schermerhorn, Marc L., et al. "The impact of Centers for Medicare and Medicaid Services high-risk criteria on outcome after carotid endarterectomy and carotid artery stenting in the SVS Vascular Registry." Journal of Vascular Surgery (2013).
  • Schold JD; et al. (2013). "Comorbidity burden and perioperative complications for living kidney donors in the United States". Clinical Journal of the American Society of Nephrology. 8 (10): 1773–1782. doi:10.2215/cjn.12311212. PMC 3789355. PMID 24071651.
  • Siracuse, Jeffrey J., et al. "Prosthetic graft infections involving the femoral artery." Journal of Vascular Surgery (2013).
  • Smith, Jillian K., et al. "Does increasing insurance improve outcomes for US cancer patients?." Journal of Surgical Research (2013).
  • Yoshida, Shunsuke, et al. "The current national criteria for carotid artery stenting overestimate its efficacy in patients who are symptomatic and at high risk." Journal of Vascular Surgery (2013).

Publications 2012

Publications 2011

Publications 2010

Publications 2009

Publications 2008

  • Al-Refaie WB, Tseng JF, Gay G, et al. (August 2008). "The impact of ethnicity on the presentation and prognosis of patients with gastric adenocarcinoma. Results from the National Cancer Data Base". Cancer. 113 (3): 461–9. doi:10.1002/cncr.23572. PMID 18553367.
  • Hill JS, McPhee JT, Messina LM, Ciocca RG, Eslami MH (July 2008). "Regionalization of abdominal aortic aneurysm repair: evidence of a shift to high-volume centers in the endovascular era". J. Vasc. Surg. 48 (1): 29–36. doi:10.1016/j.jvs.2008.02.048. PMID 18589227.
  • Csikesz N, Ricciardi R, Tseng JF, Shah SA (October 2008). "Current status of surgical management of acute cholecystitis in the United States". World J Surg. 32 (10): 2230–6. doi:10.1007/s00268-008-9679-5. PMID 18668287.
  • Csikesz NG, Simons JP, Tseng JF, Shah SA (September 2008). "Surgical specialization and operative mortality in hepato-pancreatico-biliary (HPB) surgery". J. Gastrointest. Surg. 12 (9): 1534–9. doi:10.1007/s11605-008-0566-z. PMID 18612710.
  • Csikesz NG, Tseng JF, Shah SA (August 2008). "Trends in surgical management for acute cholecystitis". Surgery. 144 (2): 283–9. doi:10.1016/j.surg.2008.03.033. PMID 18656637.
  • Eppsteiner RW, Csikesz NG, Simons JP, Tseng JF, Shah SA (October 2008). "High volume and outcome after liver resection: surgeon or center?". J. Gastrointest. Surg. 12 (10): 1709–16, discussion 1716. doi:10.1007/s11605-008-0627-3. PMID 18704600.
  • McPhee JT, Schanzer A, Messina LM, Eslami MH (December 2008). "Carotid artery stenting has increased rates of postprocedure stroke, death, and resource utilization than does carotid endarterectomy in the United States, 2005". J. Vasc. Surg. 48 (6): 1442–50, 1450.e1. doi:10.1016/j.jvs.2008.07.017. PMID 18829236.
  • Murphy MM, Simons JP, Hill JS, et al. (September 2009). "Pancreatic resection: a key component to reducing racial disparities in pancreatic adenocarcinoma". Cancer. 115 (17): 3979–90. doi:10.1002/cncr.24433. PMID 19514091.
  • Tseng JF (March 2008). "Management of serous cystadenoma of the pancreas". J. Gastrointest. Surg. 12 (3): 408–10. doi:10.1007/s11605-007-0360-3. PMID 17963014.
  • Tseng JF, Fernández-del Castillo C, Warshaw AL. Survival after medical and surgical treatment of pancreatic adenocarcinoma. In: Beger HG, Matsuno S, Cameron JL, eds. Diseases of the Pancreas: Current Surgical Therapy. Heidelberg: Springer Inc, 2008;61:695-704

Publications 2007

For more detailed information refer to the SOAR Website.

See also

Surgery

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