Stratton Parker syndrome

Stratton parker syndrome is a rare disorder characterized by short stature, wormian bones (extra cranial bones), and dextrocardia (displaced heart).[1] Other symptoms include dermatoglyphics, tooth deformities or missing teeth, abnormal kidney development, shortened limbs, mental retardation, undescended testes or cryptorchidism, and anal atresia.[1] The condition was first described by Stratton and Parker in 1989,[2] and there have been only four reported cases worldwide.[3] Two cases of the syndrome were reported by Gilles-Eric Seralini in 2010 after having been contacted in January 2009.[4]

Stratton-Parker Syndrome
Other namesShort stature wormian bones dextrocardia

Alternative names include "Growth Hormone Deficiency with Wormian Bones, Cardiac Anomaly, and Brachycamptodactyly"[5] and "Short stature wormian bones dextrocardia"[1]

References
  1. "Short stature wormian bones dextrocardia". Check Orphan. Retrieved 2011-09-27.
  2. Stratton RF, Parker MW (February 1989). "Growth hormone deficiency, wormian bones, dextrocardia, brachycamptodactyly, and other midline defects". American Journal of Medical Genetics. 32 (2): 169–73. doi:10.1002/ajmg.1320320205. PMID 2564736.
  3. Simmgen, M.; Bano, G.; Nussey, S. (2006). "Growth hormone deficiency and complex congenital abnormalities: a further case of Stratton-Parker syndrome?". Endocrine Abstracts. P86. Retrieved 2011-09-27.
  4. Mesnage, R.; Clair, E.; Spiroux De Vendomois, J.; Seralini, G. E. (2009). "Two cases of birth defects overlapping Stratton-Parker syndrome after multiple pesticide exposure". Occupational and Environmental Medicine. 67 (5): 359. doi:10.1136/oem.2009.052969. PMID 19951932.
  5. "STRATTON-PARKER SYNDROME". BioGraph. Retrieved 2011-09-27.
Classification
External resources


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