Isoniazid/rifampicin

Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis.[1] It is a fixed dose combination of isoniazid and rifampicin (rifampin).[1] It is used together with other antituberculosis medication.[1] It is taken by mouth.[1]

Isoniazid/rifampicin
Combination of
IsoniazidAnti-tuberculosis medication
RifampicinAnti-tuberculosis medication
Clinical data
Trade namesIsonaRif, Rifamate, others
Pregnancy
category
  • US: C (Risk not ruled out)
    ATC code
    Identifiers
    KEGG

    Side effects are those of the underlying medications.[1] Common side effects include poor coordination, poor appetite, nausea, numbness, and feeling tired.[2] More severe side effects include liver problems.[2] Use is generally not recommended in children.[1] It is unclear if use is safe in pregnancy.[3]

    It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[4] The wholesale cost in the developing world is about US$5.10 a month.[5] In the United Kingdom a month of medication costs the NHS about 28.11 pounds.[6]

    References
    1. WHO Model Formulary 2008 (PDF). World Health Organization. 2009. p. 142. ISBN 9789241547659. Archived (PDF) from the original on 13 December 2016. Retrieved 8 December 2016.
    2. "Isoniazid/rifampin Side Effects in Detail - Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
    3. "Isoniazid / rifampin Use During Pregnancy | Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
    4. "World Health Organization model list of essential medicines: 21st list 2019". 2019. hdl:10665/325771. Cite journal requires |journal= (help)
    5. "Rifampicin + Isoniazid". International Drug Price Indicator Guide. Retrieved 8 December 2016.
    6. British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 403. ISBN 9780857111562.
    This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.