Revefenacin
Revefenacin (trade name Yupelri) is a pharmaceutical drug for the treatment of chronic obstructive pulmonary disease (COPD). It was approved for use in the United States in 2018.[1] It was developed by Theravance Biopharma and is marketed by Mylan. Revefenacin is formulated as a solution that is nebulized and inhaled.[2]
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Trade names | Yupelri |
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Formula | C35H43N5O4 |
Molar mass | 597.760 g·mol−1 |
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Revefenacin is a bronchodilator that exerts its effect as a long-acting muscarinic antagonist.[3]
References
- "Theravance Biopharma and Mylan Receive FDA Approval for YUPELRI (revefenacin) in Adults with Chronic Obstructive Pulmonary Disease" (Press release). Mylan. November 9, 2018.
- Heo, Young-A (2018). "Revefenacin: First Global Approval". Drugs. doi:10.1007/s40265-018-1036-x. PMC 6445810. PMID 30560478.
- Donohue, James; Kerwin, Edward; Barnes, Chris; Moran, Edmund; Haumann, Brett; Pendyala, Srikanth; Crater, Glenn (2018). "Efficacy of Revefenacin, A Long-Acting Muscarinic Antagonist for Nebulized Therapy, in Copd Patients with Markers of More Severe Disease". Chest. 154 (4): 736A–737A. doi:10.1016/j.chest.2018.08.665.
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