Regression (medicine)
Regression in medicine is a characteristic of diseases to decrease in severity and/or size.
- Clinically, regression generally refers to lighter symptoms without completely disappearing. At a later point, symptoms may return. These symptoms are then called recidive.
- In cancer, regression refers to a specific decrease in the size or extent of a tumour.[1] In histopathology, histological regression is one or more areas within a tumor in which neoplastic cells have disappeared or decreased in number.[2] In melanomas, this means complete or partial disappearance from areas of the dermis (and occasionally from the epidermis), which have been replaced by fibrosis, accompanied by melanophages, new blood vessels, and a variable degree of inflammation.[2]
References
- "Regression". NCI Dictionary of Cancer Terms. National Cancer Institute. Retrieved 31 August 2017.
- Ribero, Simone; Gualano, Maria Rosaria; Osella-Abate, Simona; Scaioli, Giacomo; Bert, Fabrizio; Sanlorenzo, Martina; Balagna, Elena; Fierro, Maria Teresa; Macripò, Giuseppe; Sapino, Anna; Siliquini, Roberta; Quaglino, Pietro (2015). "Association of Histologic Regression in Primary Melanoma With Sentinel Lymph Node Status". JAMA Dermatology. 151 (12): 1301. doi:10.1001/jamadermatol.2015.2235. ISSN 2168-6068.
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