Quifenadine
Quifenadine (Russian: хифенадин, trade name: Phencarol, Фенкарол) is a 2nd generation antihistamine drug, marketed mainly in post-Soviet countries.[2][3] Chemically, it is a quinuclidine derivative.
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Trade names | Fencarol |
Other names | 3-Quinuclidinyldiphenylmethanol |
Routes of administration | Oral (tablets), IM injection |
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Bioavailability | 45% (Tmax = 1 hour)[1] |
Metabolism | Liver |
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Formula | C20H23NO |
Molar mass | 293.40 g/mol g·mol−1 |
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Indications
- Allergic rhinitis
- Acute and chronic urticaria
- Angioedema
- Dermatitis
- Atopic dermatitis
- Pruritus[1]
References
- "Fencarol (quifenadine) Tablets, for Oral Use. Full Prescribing Information". State Register of Medicines (in Russian). Retrieved 4 January 2016.
- "Quifenadine". Drugs.com. Retrieved 28 January 2014.
- Makarov, L.; Balykova, L.; Soldatova, O.; Komolyatova, V.; Serebruany, V. (2010). "The antiarrhythmic properties of quifenadine, H1-histamine receptor blocker in children with premature beats: A randomized controlled pilot trial". American Journal of Therapeutics. 17 (4): 396–401. doi:10.1097/MJT.0b013e3181a86987. PMID 19487925.
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