Profenamine

Profenamine (INN; also known as ethopropazine (BAN); trade names Parsidol, Parsidan, Parkin) is a phenothiazine derivative used as an antiparkinsonian agent[1] that has anticholinergic, antihistamine, and antiadrenergic actions. It is also used in the alleviation of the extrapyramidal syndrome induced by drugs such as other phenothiazine compounds, but, like other compounds with antimuscarinic properties, is of no value against tardive dyskinesia.

Profenamine

Clinical data
Trade names	Parsidol, Parsidan, Parkin
AHFS/Drugs.com	International Drug Names
ATC code	N04AA05 (WHO)
Pharmacokinetic data
Protein binding	93%
Elimination half-life	1 to 2 hours
Identifiers
IUPAC name N,N-Diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
CAS Number	522-00-9 N
PubChem CID	3290
IUPHAR/BPS	7181
DrugBank	DB00392 Y
ChemSpider	3174 Y
UNII	7WI4P02YN1
ChEBI	CHEBI:313639 Y
ChEMBL	ChEMBL1206 Y
CompTox Dashboard (EPA)	DTXSID2023018
ECHA InfoCard	100.007.566
Chemical and physical data
Formula	C19H24N2S
Molar mass	312.48 g·mol−1
3D model (JSmol)	Interactive image
SMILES S2c1ccccc1N(c3c2cccc3)CC(N(CC)CC)C
InChI InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3 Y Key:CDOZDBSBBXSXLB-UHFFFAOYSA-N Y
NY (what is this?)  (verify)