Oxygenation index

The oxygenation index is a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body.

A lower oxygenation index is better - this can be inferred by the equation itself. As the oxygenation of a person improves, they will be able to achieve a higher PaO2 at a lower FiO2. This would be reflected on the formula as a decrease in the numerator or an increase in the denominator - thus lowering the OI. Typically an OI threshold is set for when a neonate should be placed on ECMO, for example >40.

Equation

OI={\frac {Fi{\ce {O2}}\times M_{\text{PAW}}}{Pa{\ce {O2}}}}

[1]

$Fi{\ce {O2}}$ : Fraction of inspired oxygen, in percent;
$M_{\text{PAW}}$ : Mean airway pressure, in mmHg;
$Pa{\ce {O2}}$ : Partial pressure of oxygen in arterial blood, in mmHg.

References

Ortiz RM, Cilley RE, Bartlett RH. Extracorporeal membrane oxygenation in pediatric respiratory failure. Pediatr Clin North Am. 1987 Feb;34(1):39-46.

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[1] Ortiz RM, Cilley RE, Bartlett RH. Extracorporeal membrane oxygenation in pediatric respiratory failure. Pediatr Clin North Am. 1987 Feb;34(1):39-46.

Mechanical ventilation
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Related illness	ARDS Atelectotrauma Biotrauma Pulmonary barotrauma Pulmonary volutrauma Rheotrauma Ventilator-associated pneumonia Oxygen toxicity Ventilator-associated lung injury
Pressure	P_EEP FiO₂ Δ_P P_IP P_S P_AW P_plat
Volumes	V_T V_E V_f
Other	C_dyn C_static P_AO₂ V_D/V_T OI A-a gradient Mechanical power