Oxitropium bromide

Oxitropium bromide
Clinical data
Trade names	Oxivent, Tersigan, Tersigat, Ventilat
Other names	N-Ethylscopolammonium bromide; Ba 253; Ba 253BR-L; Ba 253Br; Hyoscine ethobromide; N-Ethylnorscopolamine methyl bromide; Scopolamine ethobromide
AHFS/Drugs.com	International Drug Names
ATC code	R03BB02 (WHO) ;
Identifiers
	IUPAC name (8r)-6β,7β-Epoxy-8-ethyl-3α-hydroxy-1αH,5αH-tropanium bromide (−)-tropate;
CAS Number	30286-75-0;
ChemSpider	16735948;
UNII	SF4NW7NH7C;
ChEMBL	ChEMBL1697846;
CompTox Dashboard (EPA)	DTXSID0023402 ;
ECHA InfoCard	100.045.543
Chemical and physical data
Formula	C19H26BrNO4
Molar mass	412.32 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [Br-].OC[C@H](c1ccccc1)C(=O)O[C@@H]2C[C@@H]3[C@H]4O[C@H]4[C@H](C2)[N+]3(C)CC;
	InChI InChI=1S/C19H26NO4.BrH/c1-3-20(2)15-9-13(10-16(20)18-17(15)24-18)23-19(22)14(11-21)12-7-5-4-6-8-12;/h4-8,13-18,21H,3,9-11H2,1-2H3;1H/q+1;/p-1/t13-,14-,15-,16+,17-,18+,20?;/m1./s1; Key:LCELQERNWLBPSY-KHSTUMNDSA-M;

Oxitropium bromide (trade names Oxivent, Tersigan) is an anticholinergic used as a bronchodilator for the treatment of asthma and chronic obstructive pulmonary disease.[1]

It was patented in 1966 and approved for medical use in 1983.[2]

References

Restrepo, R. D. (2007). "Use of inhaled anticholinergic agents in obstructive airway disease". Respiratory care. 52 (7): 833–851. PMID 17594728.
Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 447. ISBN 9783527607495.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.