Nucleus proprius of spinal cord

The nucleus proprius is a layer of the spinal cord adjacent to the substantia gelatinosa. The nucleus proprius can be found in the gray matter in all levels of the spinal cord. It constitutes the first synapse of the spinothalamic tract carrying pain and temperature sensations from peripheral nerves. Cells in this nucleus project to deeper laminae of the spinal cord, to the posterior column nuclei, and to other supraspinal relay centers including the midbrain, thalamus, and hypothalamus. Rexed laminae III and IV make up the nucleus proprius.[1]

Nucleus proprius of spinal cord
Medulla spinalis - Substantia grisea
Latinnucleus proprius medullae spinalis; laminae spinales III et IV
Anatomical terminology

The nucleus proprius (NP), along with the substantia gelatinosa of Rolando are involved in sensing pain and temperature.[2]

See also


  2. Westlund, Karin N.; Willis, William D. (2015). "Pain System". The Rat Nervous System. pp. 703–731. doi:10.1016/B978-0-12-374245-2.00025-5. ISBN 9780123742452.
  • Diagram at
  • Sławomirski J, Głuszak J (1986). "Structure and topography of the nucleus proprius cornus dorsalis of the spinal cord of horses". Pol Arch Weter. 25 (4): 131–6. PMID 3620378.

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