Nitrosoproline
Nitrosoproline is a nitroso derivative of the amino acid proline.
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IUPAC name
1-Nitroso-L-proline | |
Other names
N-Nitrosoproline; Proline nitric oxide; Proline NO | |
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Properties | |
Chemical formula |
C5H8N2O3 |
Molar mass | 144.130 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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The mixture of nitrosoproline with sodium methoxide is known as PROLI/NO (also PROLINO or ProliNO). It is an "ultrafast" nitric oxide donor which is being studied for its research and clinical applications.[1][2]
References
- Pluta RM, Rak R, Wink DA, et al. (April 2001). "Effects of nitric oxide on reactive oxygen species production and infarction size after brain reperfusion injury". Neurosurgery. 48 (4): 884–92, discussion 892–3. doi:10.1227/00006123-200104000-00039. PMID 11322449.
- Saavedra JE, Southan GJ, Davies KM, et al. (October 1996). "Localizing antithrombotic and vasodilatory activity with a novel, ultrafast nitric oxide donor". J. Med. Chem. 39 (22): 4361–5. doi:10.1021/jm960616s. PMID 8893830.
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