Dipropyltryptamine

N,N-Dipropyltryptamine (DPT, also known as "The Light") is a psychedelic drug belonging to the tryptamine family, first reported in 1973.[1] It is found either as its crystalline hydrochloride salt or as an oily or crystalline base. It has not been found to occur endogenously. It is a close structural homologue of dimethyltryptamine.

Dipropyltryptamine
Clinical data
Routes of
administration
Ingestion, inhalation, intravenous or intramuscular injection
ATC code
  • none
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
Identifiers
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H24N2
Molar mass244.38 g/mol g·mol−1
3D model (JSmol)
Melting point174.5 to 178 °C (346.1 to 352.4 °F)
  (verify)

Frequent physical effects are nausea, numbness of the tongue or throat, and pupil dilation.

Pharmacology

Studies on rodents have found that the effectiveness with which a selective 5-HT2A receptor antagonist blocks the behavioral actions of this compound strongly suggest that the 5-HT2A receptor is an important site of action for DPT, but the modulatory actions of a 5-HT1A receptor antagonist also imply a 5-HT1A-mediated component to the actions of DPT.[2]

Chemistry

DPT changes Ehrlich's reagent violet and causes the marquis reagent to turn yellow.[3]

Psychedelic properties

While dipropyltryptamine is chemically similar to dimethyltryptamine (DMT), its psychoactive effects are markedly different.[4]

While experiences of apparent entity contact may occasionally occur under the influence of DPT, the perspective is more as an observer or watcher, as contrasted to the more personal and realistic experience reported with DMT.[5]

Side effects

Negative side effects of human consumption of this drug can include increased heart rate, dizziness, anxiety, confusion, paranoia, seizure and nausea. The use of dipropyltryptamine has caused at least two deaths, both involving seizures. [6]

Religious use

DPT is used as a religious sacrament by the Temple of the True Inner Light, a New York City offshoot of the Native American Church. The Temple believes DPT and other entheogens are physical manifestations of God.[7]

United Kingdom

DPT is a Class A drug in the United Kingdom, making it illegal to possess or distribute .

United States

DPT is not scheduled at the federal level in the United States,[8] but it could be considered an analog of 5-MeO-DiPT, DMT, or DET, in which case purchase, sale, or possession could be prosecuted under the Federal Analogue Act.

Florida

"DPT (N,N-Dipropyltryptamine)" is a Schedule I controlled substance in the state of Florida making it illegal to buy, sell, or possess in Florida.[9]

Maine

DPT is a Schedule I controlled substance in the state of Maine making it illegal to buy, sell, or possess in Maine.

Sweden

DPT is illegal in Sweden as of 26 January 2016.[10]

References

  1. International Pharmacopsychiatry. 1973;8(1):104.
  2. William E. Fantegrossi, Chad J. Reissig, Elyse B. Katz, Haley L. Yarosh, Kenner C. Rice, Jerrold C. Winterb. Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents. Pharmacol Biochem Behav. 2008 January; 88(3): 358–365.
  3. Spratley, Trinette (2004). "Analytical Profiles for Five "Designer" Tryptamines" (PDF). Microgram Journal. 3 (1–2): 55. Retrieved 9 October 2013.
  4. Pinchbeck, Daniel (2003). Breaking Open The Head. Broadway Books. ISBN 0-7679-0743-4.
  5. Metzger, Richard (2003). Book of Lies - The Disinformation Guide to Magic and the Occult. The Disinformation Company Ltd. ISBN 0-9713942-7-X.
  6. Temple of the True Inner Light
  7. 21 CFR — SCHEDULES OF CONTROLLED SUBSTANCES §1308.11 Schedule I.
  8. Florida Statutes - Chapter 893 - DRUG ABUSE PREVENTION AND CONTROL
  9. "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. November 2015.
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