List of investigational sexual dysfunction drugs
This is a list of investigational sexual dysfunction drugs, or drugs that are currently under development for clinical treatment of sexual dysfunction but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
Atrophic vaginitis
- Estetrol (E4; Donesta) – estrogen receptor agonist
- Lasofoxifene (CP-336156, CP-336156-CB, Fablyn, Oporia) – selective estrogen receptor modulator
Erectile dysfunction
- HCP-1302 – undefined mechanism of action
- Nitroglycerin gel (Eroxon, Futura, MED-2001–MED-2005) – nitric oxide donor
- Tadalafil/tamsulosin (HCP-1303, CKD-397, YBH-1603)
- TT-701 (LY-2452473) – selective androgen receptor modulator
Female anorgasmia
- Testosterone low-dose intranasal (MPP-14, TBS-2, Noseafix, Tefina) – androgen receptor agonist
Female sexual dysfunction
- BP-101 – undefined mechanism of action
- Bupropion/trazodone (S1P-104, S1P-205, Lorexys, Orexa) – norepinephrine reuptake inhibitor, nicotinic acetylcholine receptor antagonist, 5-HT2A receptor antagonist, α1-adrenergic receptor antagonist, weak serotonin reuptake inhibitor
- Buspirone/testosterone (Lybridos) – 5-HT1A receptor partial agonist and androgen receptor agonist
- Lasofoxifene (CP-336156, CP-336156-CB, Fablyn, Oporia) – selective estrogen receptor modulator
- PL-6983 – selective MC4 receptor agonist
- Sildenafil/testosterone (Lybrido) – PDE5 inhibitor and androgen receptor agonist
- TGFK09SD – 5-HT1A receptor agonist
Premature ejaculation
- Clomipramine/sildenafil (CDFR-0812) – serotonin reuptake inhibitor and PDE5 inhibitor
- DA-8031 – serotonin reuptake inhibitor
- IX-01 – oxytocin receptor antagonist
- OnabotulinumtoxinA (botulinum toxin A, Botox) – acetylcholine release inhibitor
- Tramadol (BIO-301, DMI-7958, LI-301, LIF-301, Zertane) – μ-opioid receptor agonist, serotonin releasing agent, norepinephrine reuptake inhibitor, and 5-HT2C receptor antagonist
Unspecified
- Vilazodone (Viibryd, EMD-68843, SB-659746A) – 5-HT1A receptor partial agonist and serotonin reuptake inhibitor
See also
References
External links
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