List of cytochrome P450 modulators

This is a list of cytochrome P450 modulators, or inhibitors and inducers of cytochrome P450 enzymes.

EnzymeInhibitorsInducers
CYP1A1
CYP2A6
CYP2B6
CYP2C8
CYP2C9
CYP2C19
CYP2D6
CYP2E1
CYP3A4
CYP4–51
  • See Prostanoid signaling modulators and Leukotriene signaling modulators instead for eicosanoid-specific CYP450s, including:
    • CYP4F3 (leukotriene-B4 ω-hydroxylase 2)
    • CYP5A1 (thromboxane-A synthase)
    • CYP8A1 (prostacyclin synthase)
  • See the list of steroid metabolism modulators instead for steroid/sterol-specific CYP450s, including:
    • CYP7A1 (cholesterol 7α-hydroxylase)
    • CYP7B1 (25-hydroxycholesterol 7α-hydroxylase)
    • CYP8B1 (sterol 12α-hydroxylase)
    • CYP11A1 (cholesterol side-chain cleavage enzyme; P450scc)
    • CYP11B1 (steroid 11β-hydroxylase)
    • CYP11B2 (aldosterone synthase)
    • CYP17A1 (steroid 17α-hydroxylase/17,20-lyase)
    • CYP19A1 (aromatase)
    • CYP21A2 (steroid 21-hydroxylase)
    • CYP24A1 (1,25-dihydroxyvitamin D3 24-hydroxylase)
    • CYP27A1 (sterol 27-hydroxylase)
    • CYP27B1 (25-hydroxyvitamin D3 1α-hydroxylase)
    • CYP39A1 (oxysterol 7α-hydroxylase 2)
    • CYP46A1 (cholesterol 24-hydroxylase)
    • CYP51A1 (lanosterol 14α-demethylase)

See also

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