Kinin
A kinin is any of various structurally related polypeptides, such as bradykinin and kallidin.[1] They are members of the autacoid family.[2]
They act locally to induce vasodilation and contraction of smooth muscle.[3] Kinins function as mediators for inflammatory responses by triggering the immune system. They are also able to regulate cardiovascular and renal function through mediating the effects of ACE inhibitors.[4]
It is a component of the kinin-kallikrein system.
Their precursors are kininogens.[5]
In botany, the plant hormones known as cytokinins were first called kinins, but the name was changed to avoid confusion.[6]
Aspirin inhibits the activation of kallenogen by interfering with the formation of kallikrein enzyme which is essential in the process of activation.
References
- Kinins. De Gruyter. 2011. ISBN 978-3-11-025235-4.
- Kinins at the US National Library of Medicine Medical Subject Headings (MeSH)
- "Kinin" at Dorland's Medical Dictionary
- Rhaleb NE, Yang XP, Carretero OA (April 2011). "The kallikrein-kinin system as a regulator of cardiovascular and renal function". Comprehensive Physiology. 1 (2): 971–93. doi:10.1002/cphy.c100053. PMC 4685708. PMID 23737209.
- Online Medical Dictionary
- Galuszka P, Spíchal L, Kopečný D, Tarkowski P, Frébortová J, Šebela M, Frébort I (2008). "Metabolism of plant hormones cytokinins and their function in signaling, cell differentiation and plant development". Bioactive Natural Products (Part N). Studies in Natural Products Chemistry. 34. pp. 203–64. doi:10.1016/S1572-5995(08)80028-2. ISBN 978-0-444-53180-3.
External links
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Ephrin |
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Adiponectin |
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Angiotensin |
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Bradykinin |
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CGRP |
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Cholecystokinin |
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CRH |
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Cytokine | See here instead. | ||||||||
Endothelin |
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Galanin |
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Ghrelin/GHS |
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GH |
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GHRH |
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GLP |
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Glucagon |
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GnRH |
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Gonadotropin |
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Growth factor | See here instead. | ||||||||
Insulin |
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Kisspeptin |
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Leptin |
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MCH |
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Melanocortin |
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Neuropeptide FF |
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Neuropeptide S | |||||||||
Neuropeptide Y |
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Neurotensin |
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Opioid | See here instead. | ||||||||
Orexin |
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Oxytocin |
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Prolactin |
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PTH |
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Tachykinin |
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TRH |
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TSH |
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