Inosine pranobex

Inosine pranobex (BAN; also known as inosine acedoben dimepranol (INN) or methisoprinol) an antiviral drug that is a combination of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3. Inosine pranobex has no effect on viral particles itself. Instead, it acts as an immunostimulant, an analog of thymus hormones.[1] It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy.[2]

Inosine pranobex
INN: Inosine acedoben dimepranol
Chemical structures of the three components of inosine pranobex (from top to bottom: inosine, acedoben and dimethylamino isopropanol)
Combination of
InosineImmunostimulant
DimethylaminoisopropanolImmunostimulant
AcedobenImmunostimulant
Clinical data
Trade namesImunovir, Delimmun, Isoprinosine
Other namesMethisoprinol
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
PubChem CID
ChemSpider
KEGG
ECHA InfoCard100.048.313

In the UK, inosine pranobex is also indicated for mucocutaneous infections due to herpes simplex virus (type 1 and type 2) and for treatment of genital warts as adjunctive therapy to podophyllotoxin or carbon dioxide laser.[3]

References
  1. American Cancer Society. "Inosine Pranobex". Archived from the original on 23 August 2010. Retrieved 31 July 2013.
  2. Campoli-Richards DM, Sorkin EM, Heel RC (Nov 1986). "Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy". Drugs. 32 (5): 383–424. doi:10.2165/00003495-198632050-00001.
  3. "Imunovir 500mg Tablets". UK Electronic Medicines Compendium.


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