ICD-10 Chapter XVIII: Symptoms, signs and abnormal clinical and laboratory findings

ICD-10 is an international statistical classification used in health care and related industries.

ICD-10 chapters
Chapter Block Title
I A00–B99 Certain infectious and parasitic diseases
II C00–D48 Neoplasms
III D50–D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
IV E00–E90 Endocrine, nutritional and metabolic diseases
V F00–F99 Mental and behavioural disorders
VI G00–G99 Diseases of the nervous system
VII H00–H59 Diseases of the eye and adnexa
VIII H60–H95 Diseases of the ear and mastoid process
IX I00–I99 Diseases of the circulatory system
X J00–J99 Diseases of the respiratory system
XI K00–K93 Diseases of the digestive system
XII L00–L99 Diseases of the skin and subcutaneous tissue
XIII M00–M99 Diseases of the musculoskeletal system and connective tissue
XIV N00–N99 Diseases of the genitourinary system
XV O00–O99 Pregnancy, childbirth and the puerperium
XVI P00–P96 Certain conditions originating in the perinatal period
XVII Q00–Q99 Congenital malformations, deformations and chromosomal abnormalities
XVIII R00–R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
XIX S00–T98 Injury, poisoning and certain other consequences of external causes
XX V01–Y98 External causes of morbidity and mortality
XXI Z00–Z99 Factors influencing health status and contact with health services
XXII U00–U99 Codes for special purposes

Produced by the World Health Organization, it is used in several countries around the world. Some have gone on to develop their own national enhancements, building off the international version of the classification.

Chapter XVIII of ICD-10 deals with symptoms, signs, and abnormal clinical and laboratory findings. Examples of information captured using codes from Chapter XVIII include; dysuria, seizure, hyperglycaemia, and sudden infant death syndrome.

R00–R69 – Symptoms and signs

(R00–R09) Circulatory and respiratory systems

(R10–R19) Digestive system and abdomen

(R20–R23) Skin and subcutaneous tissue

(R25–R29) Nervous and musculoskeletal systems

(R30–R39) Urinary system

(R40–R46) Cognition, perception, emotional state and behaviour

(R47–R49) Speech and voice

(R50–R69) General symptoms and signs

R70–R94 – Abnormal clinical and laboratory findings, not elsewhere classified

(R70–R79) On examination of blood, without diagnosis

(R80–R82) On examination of urine, without diagnosis

(R83–R89) On examination of other body fluids, substances and tissues, without diagnosis

(R90–R94) On diagnostic imaging and in function studies, without diagnosis

R95–R99 – Ill-defined and unknown causes of mortality

  • (R95) Sudden infant death syndrome
  • (R96) Other sudden death, cause unknown
    • (R96.0) Instantaneous death
    • (R96.1) Death occurring less than 24 hours from onset of symptoms, not otherwise explained
  • (R98) Unattended death
  • (R99) Other ill-defined and unspecified causes of mortality


  • Abnormal findings on antenatal screening of mother (O28.-)
  • Certain conditions originating in the perinatal period (P00-P96)
  • Signs and symptoms classified in the body system chapters
  • Signs and symptoms of breast (N63, N64.5)

See also


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