Hypoxia preconditioned plasma

Hypoxia preconditioned plasma or hypoxia pre-conditioned plasma (abbreviated as HPP) is the (cell-free) plasma obtained after extracorporeal conditioning (i.e. culturing) of anticoagulated blood under physiological temperature (37 °C) and physiological hypoxia (1–5 %O2). Blood conditioning is typically carried out over 2 to 4 days.

Image of a prototype bioreactor device for one-step preparation and sampling of Hypoxia Preconditioned Plasma (HPP)

No high quality evidence supports its use for any medical purpose as of 2016.[1]

References
  1. Steinhoff, Gustav (2016). Regenerative Medicine - from Protocol to Patient: 5. Regenerative Therapies II. Springer. p. 377. ISBN 9783319283869.
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