Hydroxyethyl starch-induced pruritus

Hydroxyethyl starch-induced pruritus is an intense itching, lasting for as long as one year, occurring following hydroxyethyl starch intravenous infusion for vascular insufficiency.[1][2]:401There is no treatment for the itch.

Hydroxyethyl starch-induced pruritus
SpecialtyDermatology

An updated clinical review on storage in different tissues describes a pattern of storage in the reticuloendothelial system and also the skin (Wiedermann). Differential storage described via immuno-electron microscopy, see Ständer 2001 below.

See also

References
  1. Bork K (2005). "Pruritus precipitated by hydroxyethyl starch: a review". British Journal of Dermatology. 152 (1): 3–12. doi:10.1111/j.1365-2133.2004.06272.x. PMID 15656795.
  2. Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.

Further reading
  • Wiedermann CJ, Joannidis M (2014). "Accumulation of hydroxyethyl starch in human and animal tissues: a systematic review". Intensive Care Med. 40 (2): 160–70. doi:10.1007/s00134-013-3156-9. PMID 24257970.
  • Ständer S, Szépfalusi Z, Bohle B, Ständer H, Kraft D, Luger TA, Metze D (2001). "Differential storage of hydroxyethyl starch (HES) in the skin: an immunoelectron-microscopical long-term study". Cell Tissue Res. 304 (2): 261–9. doi:10.1007/s004410000324. PMID 11396719.
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