Ham test

The Ham test is a test used in the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH). The test involves placing red blood cells in mild acid; a positive result (increased RBC fragility) indicates PNH or Congenital dyserythropoietic anemia.[1][2] This is now an obsolete test for diagnosing PNH due to its low sensitivity and specificity.[3]

Ham test
Medical diagnostics

Ham's test is occasionally positive in aplastic anemia.[4]

References
  1. Ham, Thomas H. (1937). "Chronic Hemolytic Anemia with Paroxysmal Nocturnal Hemoglobinuria". New England Journal of Medicine. 217 (23): 915–7. doi:10.1056/NEJM193712022172307.
  2. MedlinePlus Encyclopedia Ham test
  3. "Paroxysmal Nocturnal Hemoglobinuria - PNH". ARUP.
  4. Ferri, Fred F. (2015). Ferri's Clinical Advisor 2016 E-Book: 5 Books in 1. Elsevier Health Sciences. p. 140. ISBN 9780323378222.


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