Fludroxycortide

Fludroxycortide (INN, BAN, JAN), also known as flurandrenolide (USAN) and flurandrenolone,[1] is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).[2][3]

Fludroxycortide
Clinical data
Trade namesCordran, Haelan
Other names6α-Fluoro-16α-hydroxyhydrocortisone 16,17-acetonide; 6α-Fluoro-11β,16α,17α,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide
AHFS/Drugs.comMicromedex Detailed Consumer Information
Routes of
administration
Topical
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.014.724
Chemical and physical data
FormulaC24H33FO6
Molar mass436.514 g/mol g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.[4][5]

References

  1. CID 15209 from PubChem
  2. Drugs.com: Fludroxycortide
  3. Patient.info: Fludroxycortide
  4. Haelan Tape Summary of Product Characteristics
  5. Nakamura, H.; Motoyoshi, S.; Ishii, K.; Seto, Y.; Shimizu, M. (1980). "Anti-inflammatory activity of a topical glucocorticoid, fludroxycortide tape in experimental animals (author's transl)". Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 76 (7): 595–607. PMID 7215997.


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