Fenethazine

Fenethazine (INN) (brand names Anergen, Contralergial, Ethysine, Etisine, Lisergan, Lysergan; former developmental code names RP-3015, SC-1627, WY-1143), or phenethazine, is a first-generation antihistamine of the phenothiazine group.[1] Promethazine, and subsequently chlorpromazine, were derived from fenethazine.[2] Fenethazine, in turn, was derived from phenbenzamine.[3]

Fenethazine
Clinical data
Other namesPhenethazinum, Phenethazine, Phenetazine; RP-3015, SC-1627, WY-1143
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.570
Chemical and physical data
FormulaC16H18N2S
Molar mass270.39 g/mol g·mol−1
3D model (JSmol)

References
  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 434–. ISBN 978-1-4757-2085-3.
  2. Florencio Zaragoza Dörwald (4 February 2013). Lead Optimization for Medicinal Chemists: Pharmacokinetic Properties of Functional Groups and Organic Compounds. John Wiley & Sons. pp. 301–. ISBN 978-3-527-64565-7.
  3. Walter Sneader (23 June 2005). Drug Discovery: A History. John Wiley & Sons. pp. 404–. ISBN 978-0-471-89979-2.



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