Effective circulating volume

The effective circulating volume (ECV) is the volume of arterial blood effectively perfusing tissue.[1][2] ECV is a dynamic quantity and not a measurable, distinct compartment.[1] This concept is useful for discussion of cardiovascular and renal physiology.

Though ECV normally varies with extracellular fluid (ECF), they become uncoupled in diseases, such as congestive heart failure (CHF) or hepatic cirrhosis. In such cases, decreased ECV may lead to volume depletion responses and edema.

Decreased ECV can stimulate renin secretion or stimulate a sympathetic nervous system response or prostaglandin release (all of which help mediate renal blood flow and glomerular filtration rate among other things).

See also

References
  1. Rennke, Helmut G.; Denker, Bradley M. (2007). Renal Pathophysiology: The Essentials. Lippincott Williams & Wilkins. p. 46. ISBN 9780781796262. Retrieved 1 November 2018.
  2. Marik, Paul Ellis (2001). Handbook of Evidence-Based Critical Care. Springer Science & Business Media. p. 110. ISBN 9780387951539. Retrieved 1 November 2018.

Sources
  • John Bullock, Michael B. Wang, Joseph Boyle. NMS Physiology. 4th ed., Lippincott Williams & Wilkins, 2001. pp 337-339.
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