Diprophylline

Diprophylline (INN)[1] or dyphylline (USAN) (trade names Dilor, Lufyllin), is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.[2][3]

Diprophylline
Clinical data
Trade namesLufyllin
Other names7-(2,3-Dihydroxy-propyl)theophylline
AHFS/Drugs.comConsumer Drug Information
MedlinePlusa682494
Pregnancy
category
  • US: C (Risk not ruled out)
    Routes of
    administration    		By mouth
    ATC code
    Legal status
    Legal status
    Identifiers
    CAS Number
    PubChem CID
    IUPHAR/BPS
    DrugBank
    ChemSpider
    UNII
    KEGG
    ChEBI
    ChEMBL
    CompTox Dashboard (EPA)
    ECHA InfoCard100.006.843
    Chemical and physical data
    FormulaC10H14N4O4
    Molar mass254.24 g/mol g·mol−1
    3D model (JSmol)
      (verify)

    See also
    • Xanthine

    References
    1. "International Non-Proprietary Names. Recommended International Non-Proprietary Names (Rec. I.N.N.): List 1" (PDF). World Health Organization. 1955. p. 188.
    2. Schwabe, U; Ukena, D; Lohse, MJ (September 1985). "Xanthine Derivatives as Antagonists at A1 and A2 Adenosine Receptors". Naunyn-Schmiedeberg's Archives of Pharmacology. 330 (3): 212–21. doi:10.1007/bf00572436. PMID 2997628.
    3. Iancu, L; Shneur, A; Cohen, H (1979). "Trials with Xanthine Derivatives in Systemic Treatment of Psoriasis". Dermatologica. 159 (1): 55–61. doi:10.1159/000250562. PMID 225216.
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