Diaminopimelic acid

Diaminopimelic acid (DAP) is an amino acid, representing an epsilon-carboxy derivative of lysine.

Diaminopimelic acid
IUPAC name
(2R,6S)-2,6-Diaminoheptanedioic acid
CAS Number
3D model (JSmol)
ECHA InfoCard 100.008.660
MeSH Diaminopimelic+acid
PubChem CID
Chemical formula
Molar mass 190.20 g/mol
Appearance white powder
Density 1.344 g/mL
Melting point 295 °C (563 °F; 568 K)
Boiling point 426.7 °C (800.1 °F; 699.8 K)
Main hazards Irritant
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

DAP is a characteristic of certain cell walls[1] of some bacteria. DAP is often found in the peptide linkages of NAM-NAG chains that make up the cell wall of gram-negative bacteria. When provided, they exhibit normal growth. When in deficiency, they still grow but with the inability to make new cell wall peptidoglycan.

This is also the attachment point for Braun's lipoprotein.[2]

See also


An alternate view of the DAP structure.


  1. Brooks, George H.; Geo F. Brooks (2007). Jawetz, Melnick & Adelberg's medical microbiology. McGraw-Hill Medical. p. 85. ISBN 0-07-147666-0.
  2. Seltmann, Guntram; Holst, Otto (2002). The Bacterial Cell Wall. Berlin: Springer. pp. 81–82. ISBN 3-540-42608-6.

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