Dexbrompheniramine/pseudoephedrine

Dexbrompheniramine/pseudoephedrine (trade name Drixoral) is a combination medication that contains the antihistamine dexbrompheniramine maleate and the decongestant pseudoephedrine sulfate. It was used to treat symptoms associated with allergies and colds such as itchy and watery eyes, runny nose, nasal and sinus congestion, and sneezing. Because it contains pseudoephedrine, its purchase in the United States was severely restricted by the Combat Methamphetamine Epidemic Act of 2005 over fears that any product containing pseudoephedrine can be used to make methamphetamine.[1]

Dexbrompheniramine/pseudoephedrine
Combination of
DexbrompheniramineAntihistamine
PseudoephedrineDecongestant
Clinical data
Trade namesDrixoral
AHFS/Drugs.comMicromedex Detailed Consumer Information
Pregnancy
category
  • US: C (Risk not ruled out)
    ATC code
    Legal status
    Legal status

    Availability

    As of 2008, Drixoral was removed from the US market by manufacturer Merck. The company's updated website attributes "changing [their] manufacturing location" for the supply disruption and currently states "it is unlikely product will be available in 2010".[2] However, the drug still appears to be available in Canada and overseas.

    References
    1. Payne, January W. (March 9, 2009). "Drixoral: Why the Allergy Medicine Isn't Available, and What to Use Instead" (html). U.S. News and World Report. Retrieved 2010-02-22.
    2. "Products Currently Unavailable" (html). Merck. 2010. Retrieved 2010-05-18.
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