Cowdry bodies

Cowdry bodies are eosinophilic or basophilic[1] nuclear inclusions composed of nucleic acid and protein seen in cells infected with Herpes simplex virus, Varicella-zoster virus, and Cytomegalovirus. They are named after Edmund Cowdry.

There are two types of intranuclear Cowdry bodies:

  • Type A (as seen in herpes simplex, VZV and Yellow fever) [2]
  • Type B (as seen in infection with poliovirus and CMV[3]), though it may seem that this is an antiquated and perhaps illusory type.[4]

Light microscopy is used for detection of Cowdry bodies.

References
  1. "Cytomegalovirus (CMV) colitis". www.pathologyoutlines.com. Retrieved 2019-04-11.
  2. "Herpes Group (Cytomegalovirus, Herpes simplex, Varicella/Zoster, Epstein-Barr)". Retrieved 2009-01-02.
  3. "B Type Inclusion - an overview | ScienceDirect Topics". www.sciencedirect.com. Retrieved 2019-11-25.
  4. http://neuropathologyblog.blogspot.com/2008/11/whiter-illusory-cowdry-b-inclusion-of.html
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