Corneal limbus

The corneal limbus is the border of the cornea and the sclera (the white of the eye). The limbus is a common site for the occurrence of corneal epithelial neoplasm. The limbus contains radially-oriented fibrovascular ridges known as the palisades of Vogt that may harbour a stem cell population.[1] The palisades of Vogt are more common in the superior and inferior quadrants around the eye.[2] Aniridia, a developmental anomaly of the iris, disrupts the normal barrier of the cornea to the conjunctival epithelial cells at the limbus.

Corneal limbus
Schematic diagram of the human eye
LatinLimbus corneae
Anatomical terminology

See also


  1. Thomas PB, Liu YH, Zhuang FF, Selvam S, Song SW, Smith RE, Trousdale MD, Yiu SC (2007). "Identification of Notch-1 expression in the limbal basal epithelium". Mol. Vis. 13: 337–44. PMC 2633467. PMID 17392684.
  2. Goldberg MF, Bron AJ (1982). "Limbal palisades of Vogt". Transactions of the American Ophthalmological Society. 80: 155–71. PMC 1312261. PMID 7182957.

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