The corneal limbus is the border of the cornea and the sclera (the white of the eye). The limbus is a common site for the occurrence of corneal epithelial neoplasm. The limbus contains radially-oriented fibrovascular ridges known as the palisades of Vogt that may harbour a stem cell population. The palisades of Vogt are more common in the superior and inferior quadrants around the eye. Aniridia, a developmental anomaly of the iris, disrupts the normal barrier of the cornea to the conjunctival epithelial cells at the limbus.
Schematic diagram of the human eye
- Thomas PB, Liu YH, Zhuang FF, Selvam S, Song SW, Smith RE, Trousdale MD, Yiu SC (2007). "Identification of Notch-1 expression in the limbal basal epithelium". Mol. Vis. 13: 337–44. PMC 2633467. PMID 17392684.
- Goldberg MF, Bron AJ (1982). "Limbal palisades of Vogt". Transactions of the American Ophthalmological Society. 80: 155–71. PMC 1312261. PMID 7182957.
- Atlas image: eye_1 at the University of Michigan Health System - "Sagittal Section Through the Eyeball"