Chorangioma

A chorangioma is a non-neoplastic, hamartoma-like growth in the placenta consisting of blood vessels.[1]

Chorangioma
Micrograph of a chorangioma (right of image). H&E stain.
SpecialtyGynecology

Signs and symptoms

Most chorangiomas are not clinically significant, i.e. they do not have an adverse effect on placental function.

The significance of a chorangioma is determined by its size and whether it is found together with other chorangiomas. Chorangiomas are significant if multiple or "large", i.e. greater than 4 cm[1] or 5 cm.[2]

Diagnosis

Large chorangiomas are diagnosed by ultrasound or MRI,[1] and confirmed by histologic examination of the placenta.

Histologically, chorangioma consist of abundant vascular channels and may be cellular.

Treatment

Small chorangiomas are not treated. Large chorangioma can be treated several ways, including chemical ablation and laser coagulation.[1]

See also

References
  1. Amer HZ, Heller DS (2010). "Chorangioma and related vascular lesions of the placenta--a review". Fetal Pediatr Pathol. 29 (4): 199–206. doi:10.3109/15513815.2010.487009. PMID 20594143.
  2. Lež C, Fures R, Hrgovic Z, Belina S, Fajdic J, Münstedt K (2010). "Chorangioma placentae". Rare Tumors. 2 (4): e67. doi:10.4081/rt.2010.e67. PMC 3019602. PMID 21234259.
Classification
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